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Angewandte Chemie (International Ed. in English)|April 25, 2018
Synthesis of Vibegron Enabled by a Ketoreductase Rationally Designed for High pH Dynamic Kinetic ReductionFeng Xu, Birgit Kosjek, Fabien L Cabirol, et al.Organic Letters|November 2, 2016
Synthesis of the GPR40 Partial Agonist MK-8666 through a Kinetically Controlled Dynamic Enzymatic Ketone ReductionAlan M Hyde, Zhijian Liu, Birgit Kosjek, et al.Bioorganic & Medicinal Chemistry Letters|November 26, 2010
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseasesMichel Gallant, Christian Beaulieu, Carl Berthelette, et al.Angewandte Chemie (International Ed. in English)|January 27, 2024
Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to BelzutifanWai Ling Cheung-Lee, Joshua N Kolev, John A McIntosh, et al.Science (New York, N.Y.)|May 7, 2026
Biocatalytic cascades enable manufacture of the macrocyclic peptide enlicitideArtis Klapars, Anna Fryszkowska, Stephanie Galanie, et al.Pageof 2