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Cancer Research
|
February 11, 2010
MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor
Bo-Sheng Pan, Grace K Y Chan, Melissa Chenard, et al.
Journal of Medicinal Chemistry
|
February 6, 2013
Discovery of 1-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide (MK-8033): A Specific c-Met/Ron dual kinase inhibitor with preferential affinity for the activated state of c-Met
Alan B Northrup, Matthew H Katcher, Michael D Altman, et al.
The Journal of Biological Chemistry
|
December 2, 2010
Genetic and pharmacological inhibition of PDK1 in cancer cells: characterization of a selective allosteric kinase inhibitor
Kumiko Nagashima, Stuart D Shumway, Sriram Sathyanarayanan, et al.
Molecular Cancer Therapeutics
|
November 24, 2021
STimulator of INterferon Genes Agonism Accelerates Antitumor Activity in Poorly Immunogenic Tumors
Samanthi A Perera, Johnny E Kopinja, Yanhong Ma, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 28, 2015
Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys
Christian Fischer, Susan L Zultanski, Hua Zhou, et al.
Journal of Medicinal Chemistry
|
May 26, 2011
Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer
Jason D Katz, James P Jewell, David J Guerin, et al.
Journal of Medicinal Chemistry
|
March 25, 2022
Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer
Wonsuk Chang, Michael D Altman, Charles A Lesburg, et al.
Science (New York, N.Y.)
|
August 22, 2020
An orally available non-nucleotide STING agonist with antitumor activity
Bo-Sheng Pan, Samanthi A Perera, Jennifer A Piesvaux, et al.
ACS Medicinal Chemistry Letters
|
July 14, 2026
Discovery of MK-2118, a Small-Molecule Agonist of STING
Timothy Henderson, Michael D Altman, Alexei V Buevich, et al.
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Showing results (11-20 of 19) with videos related to
Sort By:
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This site can display upto 19 results.
Cancer Research
|
February 11, 2010
MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor
Bo-Sheng Pan, Grace K Y Chan, Melissa Chenard, et al.
Journal of Medicinal Chemistry
|
February 6, 2013
Discovery of 1-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide (MK-8033): A Specific c-Met/Ron dual kinase inhibitor with preferential affinity for the activated state of c-Met
Alan B Northrup, Matthew H Katcher, Michael D Altman, et al.
The Journal of Biological Chemistry
|
December 2, 2010
Genetic and pharmacological inhibition of PDK1 in cancer cells: characterization of a selective allosteric kinase inhibitor
Kumiko Nagashima, Stuart D Shumway, Sriram Sathyanarayanan, et al.
Molecular Cancer Therapeutics
|
November 24, 2021
STimulator of INterferon Genes Agonism Accelerates Antitumor Activity in Poorly Immunogenic Tumors
Samanthi A Perera, Johnny E Kopinja, Yanhong Ma, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 28, 2015
Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys
Christian Fischer, Susan L Zultanski, Hua Zhou, et al.
Journal of Medicinal Chemistry
|
May 26, 2011
Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer
Jason D Katz, James P Jewell, David J Guerin, et al.
Journal of Medicinal Chemistry
|
March 25, 2022
Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer
Wonsuk Chang, Michael D Altman, Charles A Lesburg, et al.
Science (New York, N.Y.)
|
August 22, 2020
An orally available non-nucleotide STING agonist with antitumor activity
Bo-Sheng Pan, Samanthi A Perera, Jennifer A Piesvaux, et al.
ACS Medicinal Chemistry Letters
|
July 14, 2026
Discovery of MK-2118, a Small-Molecule Agonist of STING
Timothy Henderson, Michael D Altman, Alexei V Buevich, et al.
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