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NPJ Systems Biology and Applications|June 15, 2018
Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compoundsAngela Oppelt, Daniel Kaschek, Suzanna Huppelschoten, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|December 21, 2019
Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer MetastasisSijia Liu, Román González-Prieto, Mengdi Zhang, et al.
Archives of Toxicology|October 27, 2020
Comparing in vitro human liver models to in vivo human liver using RNA-SeqRajinder Gupta, Yannick Schrooders, Duncan Hauser, et al.
Cancer Research|November 13, 2014
SYK is a candidate kinase target for the treatment of advanced prostate cancerVeerander P S Ghotra, Shuning He, Geertje van der Horst, et al.
Environment International|September 1, 2018
Current EU research activities on combined exposure to multiple chemicalsStephanie K Bopp, Robert Barouki, Werner Brack, et al.
Cellular Oncology (Dordrecht, Netherlands)|January 8, 2026
Disrupting CDK9 activity suppresses triple-negative breast cancer and is enhanced by EGFR InhibitionVera E van der Noord, Ronan P McLaughlin, Jessica S Karuntu, et al.
Hepatology (Baltimore, Md.)|October 25, 2016
Stem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injuryChristopher Goldring, Daniel J Antoine, Frank Bonner, et al.
ALTEX|June 11, 2021
New approach methods (NAMs) supporting read-across: Two neurotoxicity AOP-based IATA case studiesWanda Van der Stel, Giada Carta, Julie Eakins, et al.
Oncogene|January 23, 2018
IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancerYinghui Zhang, Lynn Wester, Jichao He, et al.
ALTEX|October 16, 2025
An Alternative Safety Profiling Algorithm (ASPA) to transform next generation risk assessment into a structured and transparent processMarcel Leist, Silvia Tangianu, Femke Affourtit, et al.
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