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Molecular Pharmacology|April 30, 2013
The nuclear factor κB family member RelB facilitates apoptosis of renal epithelial cells caused by cisplatin/tumor necrosis factor α synergy by suppressing an epithelial to mesenchymal transition-like phenotypic switchGiulia Benedetti, Michiel Fokkelman, Kuan Yan, et al.Archives of Toxicology|June 1, 2015
Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicityBram Herpers, Steven Wink, Lisa Fredriksson, et al.Plos One|January 10, 2013
Automated analysis of NF-κB nuclear translocation kinetics in high-throughput screeningZi Di, Bram Herpers, Lisa Fredriksson, et al.Cellular Signalling|September 1, 2015
The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migrationMiriam C Peeters, Michiel Fokkelman, Bob Boogaard, et al.Breast Cancer Research : BCR|July 19, 2015
Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cellsBas ter Braak, Steven Wink, Esmee Koedoot, et al.British Journal of Pharmacology|July 13, 2011
cAMP signalling protects proximal tubular epithelial cells from cisplatin-induced apoptosis via activation of EpacYu Qin, Geurt Stokman, Kuan Yan, et al.Chemical Research in Toxicology|January 24, 2014
Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessmentSteven Wink, Steven Hiemstra, Suzanna Huppelschoten, et al.Journal of Cell Science|July 7, 2012
The residence time of focal adhesion kinase (FAK) and paxillin at focal adhesions in renal epithelial cells is determined by adhesion size, strength and life cycle statusSylvia E Le Dévédec, Bart Geverts, Hans de Bont, et al.Scientific Reports|August 18, 2016
Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviourMichiel Fokkelman, Hayri E Balcıoğlu, Janna E Klip, et al.Cell Biology and Toxicology|May 3, 2022
High-content high-throughput imaging reveals distinct connections between mitochondrial morphology and functionality for OXPHOS complex I, III, and V inhibitorsWanda van der Stel, Huan Yang, Sylvia E le Dévédec, et al.Pageof 21