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Journal of Medicinal Chemistry|August 13, 2013
Structure- and reactivity-based development of covalent inhibitors of the activating and gatekeeper mutant forms of the epidermal growth factor receptor (EGFR)Richard A Ward, Mark J Anderton, Susan Ashton, et al.Oncotarget|August 22, 2015
The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eµ-MYC driven B-cell lymphomaMike I Walton, Paul D Eve, Angela Hayes, et al.International Journal of Radiation Oncology, Biology, Physics|February 16, 2024
Immune Response following FLASH and Conventional Radiation in Diffuse Midline GliomaOscar Padilla, Hanna E Minns, Hong-Jian Wei, et al.Toxicology and Applied Pharmacology|June 5, 2013
Safety pharmacology--current and emerging conceptsJunnat Hamdam, Swaminathan Sethu, Trevor Smith, et al.The New England Journal of Medicine|May 6, 2014
ABT-450/r-ombitasvir and dasabuvir with or without ribavirin for HCVPeter Ferenci, David Bernstein, Jacob Lalezari, et al.Journal of Medicinal Chemistry|April 8, 2016
Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization ApproachPaolo Innocenti, Hannah L Woodward, Savade Solanki, et al.Proceedings of the National Academy of Sciences of the United States of America|December 7, 2017
Direct measurements of meltwater runoff on the Greenland ice sheet surfaceLaurence C Smith, Kang Yang, Lincoln H Pitcher, et al.Haematologica|August 31, 2019
Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammationMyriam Chimen, Aigli Evryviadou, Clare L Box, et al.Journal of Medicinal Chemistry|September 11, 2018
Introduction of a Methyl Group Curbs Metabolism of Pyrido[3,4- d]pyrimidine Monopolar Spindle 1 (MPS1) Inhibitors and Enables the Discovery of the Phase 1 Clinical Candidate N2-(2-Ethoxy-4-(4-methyl-4 H-1,2,4-triazol-3-yl)phenyl)-6-methyl- N8-neopentylpyrido[3,4- d]pyrimidine-2,8-diamine (BOS172722)Hannah L Woodward, Paolo Innocenti, Kwai-Ming J Cheung, et al.Cell Death and Differentiation|February 22, 2018
FOXQ1 controls the induced differentiation of melanocytic cellsArchis Bagati, Anna Bianchi-Smiraglia, Sudha Moparthy, et al.Pageof 117