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Bioorganic & Medicinal Chemistry Letters|December 3, 2014
The effect of pK(a) on pyrimidine/pyridine-derived histamine H4 ligandsBrad M Savall, Steven P Meduna, Jennifer Venable, et al.Journal of Medicinal Chemistry|February 6, 2014
Discovery and SAR of 6-alkyl-2,4-diaminopyrimidines as histamine H₄ receptor antagonistsBrad M Savall, Frank Chavez, Kevin Tays, et al.Bioorganic & Medicinal Chemistry Letters|September 17, 2011
Tricyclic aminopyrimidine histamine H4 receptor antagonistsBrad M Savall, Laurent Gomez, Frank Chavez, et al.Bioorganic & Medicinal Chemistry Letters|December 29, 2015
Preclinical characterization of substituted 6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one P2X7 receptor antagonistsMichael K Ameriks, Hong Ao, Nicholas I Carruthers, et al.ACS Medicinal Chemistry Letters|March 21, 2019
Discovery of Imidazo[1,2-<i>a</i>]pyrazines and Pyrazolo[1,5-<i>c</i>]pyrimidines as TARP γ-8 Selective AMPAR Negative ModulatorsBrad M Savall, Dongpei Wu, Devin M Swanson, et al.The Journal of Pharmacology and Experimental Therapeutics|March 19, 2016
Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8Michael P Maher, Nyantsz Wu, Suchitra Ravula, et al.Journal of Medicinal Chemistry|July 1, 2008
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activityCheryl A Grice, Kevin L Tays, Brad M Savall, et al.ACS Medicinal Chemistry Letters|August 22, 2018
Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8Suchitra Ravula, Brad M Savall, Nyantsz Wu, et al.Journal of Medicinal Chemistry|August 23, 2016
Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptorDevin M Swanson, Brad M Savall, Kevin J Coe, et al.Journal of Medicinal Chemistry|May 12, 2017
4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical CandidateMichael A Letavic, Brad M Savall, Brett D Allison, et al.Pageof 2