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Scientific Reports|April 1, 2021
Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapyEsmee Koedoot, Liesanne Wolters, Marcel Smid, et al.
Hepatology (Baltimore, Md.)|March 25, 2011
Diclofenac inhibits tumor necrosis factor-α-induced nuclear factor-κB activation causing synergistic hepatocyte apoptosisLisa Fredriksson, Bram Herpers, Giulia Benedetti, et al.
Molecular Cancer|August 1, 2015
Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profilingAlan M Sandercock, Steven Rust, Sandrine Guillard, et al.
Molecular Medicine (Cambridge, Mass.)|June 7, 2012
Examination of the cytotoxic and embryotoxic potential and underlying mechanisms of next-generation synthetic trioxolane and tetraoxane antimalarialsIan M Copple, Amy E Mercer, James Firman, et al.
Archives of Toxicology|June 21, 2021
New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoidsDaniela Rodrigues, Terezinha de Souza, Luke Coyle, et al.
Plos One|August 19, 2020
3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitorsLuned M Badder, Andrew J Hollins, Bram Herpers, et al.
Nature Cancer|April 26, 2022
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumorsBram Herpers, Berina Eppink, Mark I James, et al.
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