Showing results (1-10 of 10) with videos related to
Sort By:
Pageof 1
The Journal of Organic Chemistry|January 18, 2003
An efficient assembly of heterobenzazepine ring systems utilizing an intramolecular palladium-catalyzed cycloaminationBrandon J Margolis, Jacob J Swidorski, Bruce N RogersACS Medicinal Chemistry Letters|August 22, 2018
Investigating the Behavior of Published PAINS Alerts Using a Pharmaceutical Company Data SetLewis R Vidler, Ian A Watson, Brandon J Margolis, et al.ACS Medicinal Chemistry Letters|March 18, 2016
Beyond PAINs: Chemotype Sensitivity of Protein Methyltransferases in ScreensCen Gao, Brandon J Margolis, John M Strelow, et al.The Journal of Organic Chemistry|February 14, 2007
Assembly of 4-aminoquinolines via palladium catalysis: a mild and convenient alternative to SNAr methodologyBrandon J Margolis, Kimberly A Long, Dana L T Laird, et al.Journal of Biomolecular Screening|July 3, 2016
The Use of Nucleosome Substrates Improves Binding of SAM Analogs to SETD8John M Strelow, Min Xiao, Rachel N Cavitt, et al.Protein Expression and Purification|June 14, 2011
Affinity purification of a chimeric nicotinic acetylcholine receptor in the agonist and antagonist bound statesShenping Liu, Merrill S Babcock, Jacob Bode, et al.Bioorganic & Medicinal Chemistry Letters|August 9, 2023
Positive allosteric modulators of the α7 nicotinic acetylcholine receptor: SAR investigation around PNU-120596Brad A Acker, Valentina O Badescu, Mitchell B Berkenpas, et al.Bioorganic & Medicinal Chemistry Letters|January 24, 2007
Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active siteScott M Sheehan, Hans-Juergen Mest, Brian M Watson, et al.Journal of Medicinal Chemistry|October 27, 2017
Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft ModelKevin R Fales, F George Njoroge, Harold B Brooks, et al.Bioorganic & Medicinal Chemistry|October 3, 2006
Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as alpha7 nicotinic acetylcholine receptor agonistsDaniel P Walker, Donn G Wishka, David W Piotrowski, et al.Pageof 1