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Elife|February 10, 2023
Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machineryKevin Chun-Ho Ngan, Samuel M Hoenig, Hui Si Kwok, et al.Nature Communications|April 2, 2025
Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistanceAmanda L Waterbury, Jonatan Caroli, Olivia Zhang, et al.Biorxiv : the Preprint Server for Biology|September 18, 2025
A chemical-genetic interaction between PAF1 and ENL/AF9 YEATS inhibitionPaige A Barta, Leopold Garnar-Wortzel, Timothy R Bishop, et al.RSC Chemical Biology|October 27, 2025
A chemical-genetic interaction between PAF1 and ENL/AF9 YEATS inhibitionPaige A Barta, Leopold Garnar-Wortzel, Timothy R Bishop, et al.Nature Structural & Molecular Biology|February 21, 2025
CTCF/RAD21 organize the ground state of chromatin-nuclear speckle associationRuofan Yu, Shelby Roseman, Allison P Siegenfeld, et al.Biorxiv : the Preprint Server for Biology|October 3, 2025
Genetic landscape of DNMT3A R882H reveals mechanism of aberrant oligomerizationEmma M Garcia, Olivia R Lavidor, Shaunak Raval, et al.Nature Methods|September 11, 2025
Coupling CRISPR scanning with targeted chromatin accessibility profiling using a double-stranded DNA deaminaseHeejin Roh, Simon P Shen, Yan Hu, et al.Nature Communications|January 27, 2023
Chromatin complex dependencies reveal targeting opportunities in leukemiaFadi J Najm, Peter DeWeirdt, Molly M Moore, et al.Nature Chemical Biology|April 18, 2019
CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AMLMichael E Vinyard, Cindy Su, Allison P Siegenfeld, et al.The Journal of Clinical Investigation|June 21, 2016
RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongationQi Xie, Qiulian Wu, Leo Kim, et al.Pageof 5