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Frontiers in Molecular Biosciences|October 30, 2023
The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in miceVladimir M Pogorelov, Ramona M Rodriguiz, Bryan L Roth, et al.Tetrahedron Letters|June 30, 2015
Design and Synthesis of (2-(5-Chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)cyclopropyl)methanamine as a Selective Serotonin 2C AgonistJianjun Cheng, Patrick M Giguere, Wei Lv, et al.Arzneimittel-Forschung|May 27, 2006
Bioisosteric modification of salvinorin A, a potent and selective kappa-opioid receptor agonistD Jeremy Stewart, Hesham Fahmy, Bryan L Roth, et al.Nature Structural & Molecular Biology|April 20, 2026
Structural insights into coffee bitter taste perception by TAS2R43 receptorYoojoong Kim, Ryan H Gumpper, Yuxuan Zhuang, et al.Journal of Medicinal Chemistry|January 19, 2008
Binding of serotonin and N1-benzenesulfonyltryptamine-related analogs at human 5-HT6 serotonin receptors: receptor modeling studiesMałgorzata Dukat, Philip D Mosier, Renata Kolanos, et al.Pharmacology & Therapeutics|May 28, 2004
Screening the receptorome to discover the molecular targets for plant-derived psychoactive compounds: a novel approach for CNS drug discoveryBryan L Roth, Estela Lopez, Scott Beischel, et al.Proceedings of the National Academy of Sciences of the United States of America|March 16, 2007
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligandBlaine N Armbruster, Xiang Li, Mark H Pausch, et al.American Journal of Physiology. Cell Physiology|June 25, 2010
RNA interference screen for RGS protein specificity at muscarinic and protease-activated receptors reveals bidirectional modulation of signalingGeneviève Laroche, Patrick M Giguère, Bryan L Roth, et al.Scientific Reports|December 8, 2016
Structure and dynamics of a constitutively active neurotensin receptorBrian E Krumm, Sangbae Lee, Supriyo Bhattacharya, et al.Nature|February 22, 2018
Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidoneSheng Wang, Tao Che, Anat Levit, et al.Pageof 43