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Bioorganic & Medicinal Chemistry Letters|August 10, 2010
N-tetrahydrothiochromenoisoxazole-1-carboxamides as selective antagonists of cloned human 5-HT2BYoon Jin Kwon, Simon Saubern, James M Macdonald, et al.Plos One|March 26, 2013
The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptorBryan L Roth, Simon Gibbons, Warunya Arunotayanun, et al.Bioorganic & Medicinal Chemistry|December 8, 2004
Synthesis and receptor assay of aromatic-ethynyl-aromatic derivatives with potent mGluR5 antagonist activityDavid Alagille, Ronald M Baldwin, Bryan L Roth, et al.Beilstein Journal of Organic Chemistry|December 5, 2012
trans-2-(2,5-Dimethoxy-4-iodophenyl)cyclopropylamine and trans-2-(2,5-dimethoxy-4-bromophenyl)cyclopropylamine as potent agonists for the 5-HT(2) receptor familyAdam Pigott, Stewart Frescas, John D McCorvy, et al.Bioorganic & Medicinal Chemistry Letters|August 3, 2005
SAR of psilocybin analogs: discovery of a selective 5-HT 2C agonistHoward Sard, Govindaraj Kumaran, Cynthia Morency, et al.Bioorganic & Medicinal Chemistry Letters|February 3, 2005
Functionalization at position 3 of the phenyl ring of the potent mGluR5 noncompetitive antagonists MPEPDavid Alagille, Ronald M Baldwin, Bryan L Roth, et al.The Journal of Biological Chemistry|December 24, 2008
Ribosomal S6 kinase 2 directly phosphorylates the 5-hydroxytryptamine 2A (5-HT2A) serotonin receptor, thereby modulating 5-HT2A signalingRyan T Strachan, Douglas J Sheffler, Belinda Willard, et al.Psychopharmacology|March 15, 2005
The highly efficacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: is M1 agonism a pre-requisite for mimicking clozapine's actions?Marilyn A Davies, Beth Ann Compton-Toth, Sandra J Hufeisen, et al.Cell|December 4, 2024
Structure-guided design of a peripherally restricted chemogenetic systemHye Jin Kang, Brian E Krumm, Adrien Tassou, et al.Nature Communications|August 5, 2024
A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated stateKevin M Knight, Brian E Krumm, Nicholas J Kapolka, et al.Pageof 43