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Science (New York, N.Y.)|May 16, 2024
AlphaFold2 structures guide prospective ligand discoveryJiankun Lyu, Nicholas Kapolka, Ryan Gumpper, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 2, 2016
Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activationPeter M Grace, Keith A Strand, Erika L Galer, et al.
Science (New York, N.Y.)|March 23, 2013
Structural basis for molecular recognition at serotonin receptorsChong Wang, Yi Jiang, Jinming Ma, et al.
Biorxiv : the Preprint Server for Biology|October 9, 2023
A suite of engineered mice for interrogating psychedelic drug actionsYi-Ting Chiu, Ariel Y Deutch, Wei Wang, et al.
Neuron|July 19, 2025
The polypharmacology of psychedelics reveals multiple targets for potential therapeuticsManish K Jain, Ryan H Gumpper, Samuel T Slocum, et al.
Journal of Medicinal Chemistry|February 19, 2026
Large Library Docking for PolypharmacologyYujin Wu, Seth Vigneron, Joao Braz, et al.
Nature|December 14, 2012
Automated design of ligands to polypharmacological profilesJérémy Besnard, Gian Filippo Ruda, Vincent Setola, et al.
ACS Chemical Biology|April 26, 2013
An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1Kyle D Konze, Anqi Ma, Fengling Li, et al.
ACS Pharmacology & Translational Science|March 15, 2019
DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in VivoKaren J Thompson, Elham Khajehali, Sophie J Bradley, et al.
Research Square|July 24, 2020
COVID-19: Famotidine, Histamine, Mast Cells, and MechanismsRobert W Malone, Philip Tisdall, Philip Fremont-Smith, et al.
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