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Methods in Molecular Biology (Clifton, N.J.)|July 16, 2013
ASC speck formation as a readout for inflammasome activationAndrea Stutz, Gabor L Horvath, Brian G Monks, et al.The Journal of Biological Chemistry|July 2, 2010
MD-2 residues tyrosine 42, arginine 69, aspartic acid 122, and leucine 125 provide species specificity for lipid IVAJianmin Meng, Joshua R Drolet, Brian G Monks, et al.The Journal of Biological Chemistry|September 10, 2003
Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transductionAlberto Visintin, Eicke Latz, Brian G Monks, et al.Journal of Immunology (Baltimore, Md. : 1950)|November 8, 2005
Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2Alberto Visintin, Kristen A Halmen, Eicke Latz, et al.Journal of Leukocyte Biology|September 2, 2006
MD-2 expression is not required for cell surface targeting of Toll-like receptor 4 (TLR4)Alberto Visintin, Kristen A Halmen, Naseema Khan, et al.The Journal of Biological Chemistry|February 18, 2011
Natural loss-of-function mutation of myeloid differentiation protein 88 disrupts its ability to form MyddosomesKamalpreet Nagpal, Theo S Plantinga, Cherilyn M Sirois, et al.Journal of Immunology (Baltimore, Md. : 1950)|October 8, 2005
The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-ISimon Rothenfusser, Nadege Goutagny, Gary DiPerna, et al.The Journal of Biological Chemistry|September 27, 2002
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transductionEicke Latz, Alberto Visintin, Egil Lien, et al.Nature Chemical Biology|April 23, 2013
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosisErik C Hett, Louise H Slater, Kevin G Mark, et al.Pageof 3