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The Journal of Pharmacology and Experimental Therapeutics
|
March 19, 2016
Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8
Michael P Maher, Nyantsz Wu, Suchitra Ravula, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors
Kiev S Ly, Michael A Letavic, John M Keith, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
July 17, 2015
Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia
Pascal Bonaventure, Jonathan Shelton, Sujin Yun, et al.
Journal of Medicinal Chemistry
|
February 9, 2023
Discovery of a Series of Substituted 1<i>H</i>-((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators
Christine F Gelin, Brice Stenne, Heather Coate, et al.
ACS Medicinal Chemistry Letters
|
October 16, 2020
Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793
Cathy Préville, Pascal Bonaventure, Tatiana Koudriakova, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists
Michael A Letavic, Brian Lord, Francois Bischoff, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
May 10, 2012
Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder
Pascal Bonaventure, Christine Dugovic, Michelle Kramer, et al.
Journal of Medicinal Chemistry
|
June 19, 2015
Novel Octahydropyrrolo[3,4-c]pyrroles Are Selective Orexin-2 Antagonists: SAR Leading to a Clinical Candidate
Michael A Letavic, Pascal Bonaventure, Nicholas I Carruthers, et al.
ACS Medicinal Chemistry Letters
|
August 22, 2018
Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8
Suchitra Ravula, Brad M Savall, Nyantsz Wu, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 13, 2010
Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonists
Emily M Stocking, Leah Aluisio, John R Atack, et al.
Page
of 7
Search research articles
Search
Showing results (51-60 of 70) with videos related to
Sort By:
Page
of 7
The Journal of Pharmacology and Experimental Therapeutics
|
March 19, 2016
Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8
Michael P Maher, Nyantsz Wu, Suchitra Ravula, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors
Kiev S Ly, Michael A Letavic, John M Keith, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
July 17, 2015
Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia
Pascal Bonaventure, Jonathan Shelton, Sujin Yun, et al.
Journal of Medicinal Chemistry
|
February 9, 2023
Discovery of a Series of Substituted 1<i>H</i>-((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators
Christine F Gelin, Brice Stenne, Heather Coate, et al.
ACS Medicinal Chemistry Letters
|
October 16, 2020
Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793
Cathy Préville, Pascal Bonaventure, Tatiana Koudriakova, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists
Michael A Letavic, Brian Lord, Francois Bischoff, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
May 10, 2012
Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder
Pascal Bonaventure, Christine Dugovic, Michelle Kramer, et al.
Journal of Medicinal Chemistry
|
June 19, 2015
Novel Octahydropyrrolo[3,4-c]pyrroles Are Selective Orexin-2 Antagonists: SAR Leading to a Clinical Candidate
Michael A Letavic, Pascal Bonaventure, Nicholas I Carruthers, et al.
ACS Medicinal Chemistry Letters
|
August 22, 2018
Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8
Suchitra Ravula, Brad M Savall, Nyantsz Wu, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 13, 2010
Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonists
Emily M Stocking, Leah Aluisio, John R Atack, et al.
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of 7