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Journal of Medicinal Chemistry
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April 25, 2020
Positional Analogue Scanning: An Effective Strategy for Multiparameter Optimization in Drug Design
Lewis D Pennington, Brian M Aquila, Younggi Choi, et al.
Expert Opinion on Therapeutic Patents
|
May 19, 2015
Small molecule inhibitor of apoptosis proteins antagonists: a patent review
Alexander W Hird, Brian M Aquila, Edward J Hennessy, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 24, 2012
Discovery of aminopiperidine-based Smac mimetics as IAP antagonists
Edward J Hennessy, Jamal C Saeh, Li Sha, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 18, 2014
Structure-based design and synthesis of tricyclic IAP (Inhibitors of Apoptosis Proteins) inhibitors
Alexander W Hird, Brian M Aquila, Michael H Block, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 13, 2008
Pyridyl and thiazolyl bisamide CSF-1R inhibitors for the treatment of cancer
David A Scott, Brian M Aquila, Geraldine A Bebernitz, et al.
Journal of Medicinal Chemistry
|
November 14, 2024
Design and Synthesis of Acyclic Boronic Acid Arginase Inhibitors
Jason D Shields, Brian M Aquila, David Emmons, et al.
Journal of Medicinal Chemistry
|
November 22, 2024
Discovery of (2<i>R</i>,4<i>R</i>)-4-((<i>S</i>)-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer
Scott N Mlynarski, Brian M Aquila, Susan Cantin, et al.
Journal of Medicinal Chemistry
|
December 11, 2013
Discovery of a novel class of dimeric Smac mimetics as potent IAP antagonists resulting in a clinical candidate for the treatment of cancer (AZD5582)
Edward J Hennessy, Ammar Adam, Brian M Aquila, et al.
Nature Communications
|
December 19, 2018
Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia
Adriana E Tron, Matthew A Belmonte, Ammar Adam, et al.
Page
of 1
Search research articles
Search
Showing results (1-10 of 9) with videos related to
Sort By:
Page
of 1
Journal of Medicinal Chemistry
|
April 25, 2020
Positional Analogue Scanning: An Effective Strategy for Multiparameter Optimization in Drug Design
Lewis D Pennington, Brian M Aquila, Younggi Choi, et al.
Expert Opinion on Therapeutic Patents
|
May 19, 2015
Small molecule inhibitor of apoptosis proteins antagonists: a patent review
Alexander W Hird, Brian M Aquila, Edward J Hennessy, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 24, 2012
Discovery of aminopiperidine-based Smac mimetics as IAP antagonists
Edward J Hennessy, Jamal C Saeh, Li Sha, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 18, 2014
Structure-based design and synthesis of tricyclic IAP (Inhibitors of Apoptosis Proteins) inhibitors
Alexander W Hird, Brian M Aquila, Michael H Block, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 13, 2008
Pyridyl and thiazolyl bisamide CSF-1R inhibitors for the treatment of cancer
David A Scott, Brian M Aquila, Geraldine A Bebernitz, et al.
Journal of Medicinal Chemistry
|
November 14, 2024
Design and Synthesis of Acyclic Boronic Acid Arginase Inhibitors
Jason D Shields, Brian M Aquila, David Emmons, et al.
Journal of Medicinal Chemistry
|
November 22, 2024
Discovery of (2<i>R</i>,4<i>R</i>)-4-((<i>S</i>)-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer
Scott N Mlynarski, Brian M Aquila, Susan Cantin, et al.
Journal of Medicinal Chemistry
|
December 11, 2013
Discovery of a novel class of dimeric Smac mimetics as potent IAP antagonists resulting in a clinical candidate for the treatment of cancer (AZD5582)
Edward J Hennessy, Ammar Adam, Brian M Aquila, et al.
Nature Communications
|
December 19, 2018
Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia
Adriana E Tron, Matthew A Belmonte, Ammar Adam, et al.
Page
of 1