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Future Medicinal Chemistry|June 20, 2020
Targeting epigenetic protein-protein interactions with small-molecule inhibitorsBrian M Linhares, Jolanta Grembecka, Tomasz CierpickiEuropean Journal of Medicinal Chemistry|September 4, 2020
Covalent and noncovalent constraints yield a figure eight-like conformation of a peptide inhibiting the menin-MLL interactionPaulina Fortuna, Brian M Linhares, Trupta Purohit, et al.Journal of the American Chemical Society|August 27, 2024
Development of Ligands and Degraders Targeting MAGE-A3Ke Li, Mackenzie W Krone, Arseniy Butrin, et al.Proceedings of the National Academy of Sciences of the United States of America|October 20, 2020
Unexpected specificity within dynamic transcriptional protein-protein complexesMadeleine J Henley, Brian M Linhares, Brittany S Morgan, et al.Nature Communications|November 17, 2022
Increased slow dynamics defines ligandability of BTB domainsVladlena Kharchenko, Brian M Linhares, Megan Borregard, et al.ACS Chemical Biology|August 4, 2018
GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding ModeHyo Je Cho, Hao Li, Brian M Linhares, et al.Angewandte Chemie (International Ed. in English)|February 13, 2024
Development of a Small Molecule Downmodulator for the Transcription Factor BrachyuryDavis H Chase, Adrian M Bebenek, Pengju Nie, et al.Journal of Medicinal Chemistry|July 4, 2018
Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug DesignHuimin Cheng, Brian M Linhares, Wenbo Yu, et al.Journal of Medicinal Chemistry|May 9, 2018
Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia InteractionDmitry Borkin, Szymon Klossowski, Jonathan Pollock, et al.Proceedings of the National Academy of Sciences of the United States of America|July 20, 2016
Flexible, symmetry-directed approach to assembling protein cagesAaron Sciore, Min Su, Philipp Koldewey, et al.Pageof 2