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Trends in Pharmacological Sciences|June 11, 2025
At last: the mitochondrial pyruvate carrier structure revealed!Brian N Finck, Christy M Hadfield, Kyle S McCommisCellular and Molecular Gastroenterology and Hepatology|January 29, 2019
Treating Hepatic Steatosis and Fibrosis by Modulating Mitochondrial Pyruvate MetabolismKyle S McCommis, Brian N FinckThe Biochemical Journal|March 10, 2015
Mitochondrial pyruvate transport: a historical perspective and future research directionsKyle S McCommis, Brian N FinckBiomolecules|February 25, 2023
The Hepatic Mitochondrial Pyruvate Carrier as a Regulator of Systemic Metabolism and a Therapeutic Target for Treating Metabolic DiseaseKyle S McCommis, Brian N FinckBiorxiv : the Preprint Server for Biology|July 29, 2024
Computational structural prediction and chemical inhibition of the human mitochondrial pyruvate carrier protein heterodimer complexChristy M Hadfield, John K Walker, Chris Arnatt, et al.Hepatology Communications|February 7, 2018
Treating fatty liver disease by modulating mitochondrial pyruvate metabolismJerry R Colca, William G McDonald, Kyle S McCommis, et al.Endocrinology|November 11, 2017
Inhibition of the Mitochondrial Pyruvate Carrier by TolylfluanidYana Chen, Kyle S McCommis, Daniel Ferguson, et al.Biomedicines|February 25, 2022
Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual ScreeningLamees Hegazy, Lauren E Gill, Kelly D Pyles, et al.The Journal of Biological Chemistry|July 21, 2019
The peptide hormone adropin regulates signal transduction pathways controlling hepatic glucose metabolism in a mouse model of diet-induced obesitySu Gao, Sarbani Ghoshal, Liyan Zhang, et al.Cell Metabolism|September 8, 2015
Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine CyclingKyle S McCommis, Zhouji Chen, Xiaorong Fu, et al.Pageof 22