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Journal of the American Chemical Society
|
August 4, 2005
Total synthesis of thiostrepton. Assembly of key building blocks and completion of the synthesis
K C Nicolaou, Mark Zak, Brian S Safina, et al.
Journal of the American Chemical Society
|
August 4, 2005
Total synthesis of thiostrepton. Retrosynthetic analysis and construction of key building blocks
K C Nicolaou, Brian S Safina, Mark Zak, et al.
ACS Medicinal Chemistry Letters
|
September 27, 2017
Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles
Brian S Safina, Richard L Elliott, Andrew K Forrest, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 23, 2013
Identification of GNE-293, a potent and selective PI3Kδ inhibitor: navigating in vitro genotoxicity while improving potency and selectivity
Brian S Safina, Zachary K Sweeney, Jun Li, et al.
Journal of Medicinal Chemistry
|
November 8, 2017
Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers
Stephen J Gregson, Luke A Masterson, Binqing Wei, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models
Thilo Focken, Shifeng Liu, Navjot Chahal, et al.
Cell Reports
|
September 21, 2018
Selective Na<sub>V</sub>1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain
Girish Bankar, Samuel J Goodchild, Sarah Howard, et al.
Journal of Medicinal Chemistry
|
March 30, 2018
Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling
Huifen Chen, Matthew Volgraf, Steven Do, et al.
Journal of Medicinal Chemistry
|
September 1, 2012
Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumors
James F Blake, Rui Xu, Josef R Bencsik, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 8, 2012
Potent and selective inhibitors of PI3Kδ: obtaining isoform selectivity from the affinity pocket and tryptophan shelf
Daniel P Sutherlin, Stewart Baker, Angelina Bisconte, et al.
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Search research articles
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Showing results (1-10 of 21) with videos related to
Sort By:
Page
of 3
Journal of the American Chemical Society
|
August 4, 2005
Total synthesis of thiostrepton. Assembly of key building blocks and completion of the synthesis
K C Nicolaou, Mark Zak, Brian S Safina, et al.
Journal of the American Chemical Society
|
August 4, 2005
Total synthesis of thiostrepton. Retrosynthetic analysis and construction of key building blocks
K C Nicolaou, Brian S Safina, Mark Zak, et al.
ACS Medicinal Chemistry Letters
|
September 27, 2017
Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles
Brian S Safina, Richard L Elliott, Andrew K Forrest, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 23, 2013
Identification of GNE-293, a potent and selective PI3Kδ inhibitor: navigating in vitro genotoxicity while improving potency and selectivity
Brian S Safina, Zachary K Sweeney, Jun Li, et al.
Journal of Medicinal Chemistry
|
November 8, 2017
Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers
Stephen J Gregson, Luke A Masterson, Binqing Wei, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models
Thilo Focken, Shifeng Liu, Navjot Chahal, et al.
Cell Reports
|
September 21, 2018
Selective Na<sub>V</sub>1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain
Girish Bankar, Samuel J Goodchild, Sarah Howard, et al.
Journal of Medicinal Chemistry
|
March 30, 2018
Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling
Huifen Chen, Matthew Volgraf, Steven Do, et al.
Journal of Medicinal Chemistry
|
September 1, 2012
Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumors
James F Blake, Rui Xu, Josef R Bencsik, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 8, 2012
Potent and selective inhibitors of PI3Kδ: obtaining isoform selectivity from the affinity pocket and tryptophan shelf
Daniel P Sutherlin, Stewart Baker, Angelina Bisconte, et al.
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of 3