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Bioorganic & Medicinal Chemistry Letters|August 12, 2008
Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolaseJohn M Keith, Richard Apodaca, Wei Xiao, et al.Bioorganic & Medicinal Chemistry Letters|April 28, 2020
Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγtChristian Gege, Michael Albers, Olaf Kinzel, et al.The Journal of Biological Chemistry|June 19, 2014
Targeting the ion channel Kv1.3 with scorpion venom peptides engineered for potency, selectivity, and half-lifeWilson Edwards, Wai-Ping Fung-Leung, Chichi Huang, et al.Journal of Medicinal Chemistry|August 14, 2020
Design, Synthesis, and Preclinical Evaluation of 3-Methyl-6-(5-thiophenyl)-1,3-dihydro-imidazo[4,5-<i>b</i>]pyridin-2-ones as Selective GluN2B Negative Allosteric Modulators for the Treatment of Mood DisordersChrista C Chrovian, Akinola Soyode-Johnson, Brice Stenne, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 AntagonistsMichael A Letavic, Brian Lord, Francois Bischoff, et al.Blood|April 11, 2013
CXCL13 plus interleukin 10 is highly specific for the diagnosis of CNS lymphomaJames L Rubenstein, Valerie S Wong, Cigall Kadoch, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Aryl Piperazinyl Ureas as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) in Rat, Dog, and PrimateJohn M Keith, Rich Apodaca, Mark Tichenor, et al.Bioorganic & Medicinal Chemistry Letters|April 24, 2019
3-Substituted Quinolines as RORγt Inverse AgonistsVirginia M Tanis, Hariharan Venkatesan, Maxwell D Cummings, et al.Journal of Medicinal Chemistry|December 7, 2017
A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical CandidateChrista C Chrovian, Akinola Soyode-Johnson, Alexander A Peterson, et al.Journal of Medicinal Chemistry|August 23, 2016
Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptorDevin M Swanson, Brad M Savall, Kevin J Coe, et al.Pageof 8