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Brian Spencer

Showing results (101-110 of 111) with videos related to

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Nature Cell Biology|August 17, 2010
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibitionAlessandro Luciani, Valeria Rachela Villella, Speranza Esposito, et al.
Journal of Molecular Biology|June 24, 2026
Structural basis for the pro-amyloidogenic action and ligand binding of a novel W72R variant of human apolipoprotein A-ITatiana Prokaeva, Shobini Jayaraman, Elena S Klimtchuk, et al.
Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis|May 16, 2022
A novel substitution of proline (P32L) destabilises β2-microglobulin inducing hereditary systemic amyloidosisTatiana Prokaeva, Tracy Joshi, Elena S Klimtchuk, et al.
Cell Metabolism|October 9, 2014
Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagyAmy N Dubinsky, Somasish Ghosh Dastidar, Cynthia L Hsu, et al.
Neurobiology of Disease|August 25, 2019
Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivoDarren J Schofield, Lorraine Irving, Laura Calo, et al.
The Journal of Experimental Medicine|March 2, 2021
Preclinical validation of a potent γ-secretase modulator for Alzheimer's disease preventionKevin D Rynearson, Moorthi Ponnusamy, Olga Prikhodko, et al.
Brain : a Journal of Neurology|September 29, 2016
A de novo compound targeting α-synuclein improves deficits in models of Parkinson's diseaseWolfgang Wrasidlo, Igor F Tsigelny, Diana L Price, et al.
JAMA Cardiology|September 10, 2025
Transthyretin Cardiac Amyloidosis in Older Black and Hispanic Individuals With Heart FailureFrederick L Ruberg, Sergio Teruya, Stephen Helmke, et al.
Scientific Reports|November 20, 2019
Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated DysfunctionsGergely Tóth, Thomas Neumann, Amandine Berthet, et al.
NPJ Parkinson'S Disease|August 22, 2025
A brain-shuttled antibody targeting alpha synuclein aggregates for the treatment of synucleinopathiesSungwon An, John J McInnis, Dongin Kim, et al.
Pageof 12

Showing results (101-110 of 111) with videos related to

Sort By:
Pageof 12
Nature Cell Biology|August 17, 2010
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibitionAlessandro Luciani, Valeria Rachela Villella, Speranza Esposito, et al.
Journal of Molecular Biology|June 24, 2026
Structural basis for the pro-amyloidogenic action and ligand binding of a novel W72R variant of human apolipoprotein A-ITatiana Prokaeva, Shobini Jayaraman, Elena S Klimtchuk, et al.
Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis|May 16, 2022
A novel substitution of proline (P32L) destabilises β2-microglobulin inducing hereditary systemic amyloidosisTatiana Prokaeva, Tracy Joshi, Elena S Klimtchuk, et al.
Cell Metabolism|October 9, 2014
Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagyAmy N Dubinsky, Somasish Ghosh Dastidar, Cynthia L Hsu, et al.
Neurobiology of Disease|August 25, 2019
Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivoDarren J Schofield, Lorraine Irving, Laura Calo, et al.
The Journal of Experimental Medicine|March 2, 2021
Preclinical validation of a potent γ-secretase modulator for Alzheimer's disease preventionKevin D Rynearson, Moorthi Ponnusamy, Olga Prikhodko, et al.
Brain : a Journal of Neurology|September 29, 2016
A de novo compound targeting α-synuclein improves deficits in models of Parkinson's diseaseWolfgang Wrasidlo, Igor F Tsigelny, Diana L Price, et al.
JAMA Cardiology|September 10, 2025
Transthyretin Cardiac Amyloidosis in Older Black and Hispanic Individuals With Heart FailureFrederick L Ruberg, Sergio Teruya, Stephen Helmke, et al.
Scientific Reports|November 20, 2019
Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated DysfunctionsGergely Tóth, Thomas Neumann, Amandine Berthet, et al.
NPJ Parkinson'S Disease|August 22, 2025
A brain-shuttled antibody targeting alpha synuclein aggregates for the treatment of synucleinopathiesSungwon An, John J McInnis, Dongin Kim, et al.
Pageof 12