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Journal of Biomolecular NMR|September 12, 2006
Identification of individual protein-ligand NOEs in the limit of intermediate exchangeMikhail Reibarkh, Thomas J Malia, Brian T Hopkins, et al.
Organic Letters|May 25, 2002
ROMPgel-supported triphenylphosphine with potential application in parallel synthesisErik Arstad, Anthony G M Barrett, Brian T Hopkins, et al.
Organic Letters|February 28, 2004
Parallel synthesis of terminal alkynes using a ROMPgel-supported ethyl 1-diazo-2-oxopropylphosphonateAnthony G M Barrett, Brian T Hopkins, Andrew C Love, et al.
Circulation|February 9, 2026
Involvement of Btk in Cardiovascular Disease and Its Therapeutic TargetingPhilipp von Hundelshausen, Wolfgang Siess, Rundan Duan, et al.
The Journal of Organic Chemistry|May 24, 2019
Utilization of Cyclic Amides as Masked Aldehyde Equivalents in Reductive Amination ReactionsRobin J Prince, Fang Gao, Jessica E Pazienza, et al.
Drug Design, Development and Therapy|April 22, 2026
First-in-Human Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Oral Doses of BIIB091, an Oral BTK Inhibitor, in Healthy Adult ParticipantsHui-Hsin Tsai, Yi Gu, Katherine Riester, et al.
Bioorganic & Medicinal Chemistry Letters|January 18, 2022
Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitorsBin Ma, Claire M Metrick, Chungang Gu, et al.
Acta Neuropathologica|March 18, 2022
BTK inhibition limits B-cell-T-cell interaction through modulation of B-cell metabolism: implications for multiple sclerosis therapyRui Li, Hao Tang, Jeremy C Burns, et al.
Journal of Medicinal Chemistry|March 12, 2024
The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-N-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)imidazo[1,2-a]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic StrokeRyan Evans, Philippe N Bolduc, Magnus Pfaffenbach, et al.
Protein Science : a Publication of the Protein Society|January 7, 2010
Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinasesDouglas J Marcotte, Yu-Ting Liu, Robert M Arduini, et al.
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