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Nature Chemistry|February 12, 2020
Electronic complementarity permits hindered butenolide heterodimerization and discovery of novel cGAS/STING pathway antagonistsBenjamin J Huffman, Shuming Chen, J Luca Schwarz, et al.Biochemistry|June 22, 2005
Mutational, structural, and kinetic evidence for a dissociative mechanism in the GDP-mannose mannosyl hydrolase reactionZuyong Xia, Hugo F Azurmendi, Luke L Lairson, et al.ACS Combinatorial Science|June 18, 2016
High-Throughput Screening Uncovers Novel Botulinum Neurotoxin Inhibitor ChemotypesKristin M Bompiani, Dejan Caglič, Michelle C Krutein, et al.Biochemistry|October 15, 2009
NMR spectroscopic characterization of the sialyltransferase CstII from Campylobacter jejuni: histidine 188 is the general basePatrick H W Chan, Luke L Lairson, Ho Jun Lee, et al.European Journal of Medicinal Chemistry|August 24, 2022
Synthesis and biological evaluation of novel FiVe1 derivatives as potent and selective agents for the treatment of mesenchymal cancersFrancisco Martínez-Peña, Aaron D Pearson, Eileen L Tang, et al.Bioorganic & Medicinal Chemistry Letters|May 8, 2018
Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinomaJustin Anglin, Reza Beheshti Zavareh, Philipp N Sander, et al.Nature Structural & Molecular Biology|January 20, 2004
Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analogCecilia P C Chiu, Andrew G Watts, Luke L Lairson, et al.Nature Methods|July 25, 2006
High-throughput screening methodology for the directed evolution of glycosyltransferasesAmir Aharoni, Karena Thieme, Cecilia P C Chiu, et al.Bioorganic Chemistry|January 28, 2021
Discovery and SAR studies of 3-amino-4-(phenylsulfonyl)tetrahydrothiophene 1,1-dioxides as non-electrophilic antioxidant response element (ARE) activatorsJeyun Jo, Lara Ibrahim, Jonathan Iaconelli, et al.Proceedings of the National Academy of Sciences of the United States of America|November 1, 2017
A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancersMichael J Bollong, Mika Pietilä, Aaron D Pearson, et al.Pageof 7