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Bronwyn G Siim

Showing results (1-10 of 13) with videos related to

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Nature Reviews. Drug Discovery|October 4, 2003
HIF-1 as a target for drug developmentAmato Giaccia, Bronwyn G Siim, Randall S Johnson
Radiation Research|May 27, 2004
Oxygen dependence of the metabolic activation and cytotoxicity of tirapazamine: implications for extravascular transport and activity in tumorsKevin O Hicks, Bronwyn G Siim, Frederik B Pruijn, et al.
Journal of Natural Products|May 26, 2010
Regio- and stereospecific synthesis of mono-beta-d-glucuronic acid derivatives of combretastatin A-1Rajendra P Tanpure, Tracy E Strecker, David J Chaplin, et al.
Cancer Chemotherapy and Pharmacology|December 24, 2002
Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)Bronwyn G Siim, Alan E Lee, Sahar Shalal-Zwain, et al.
International Journal of Radiation Oncology, Biology, Physics|September 18, 2007
Oxygen dependence and extravascular transport of hypoxia-activated prodrugs: comparison of the dinitrobenzamide mustard PR-104A and tirapazamineKevin O Hicks, Hilary Myint, Adam V Patterson, et al.
Journal of Medicinal Chemistry|November 16, 2007
Pharmacokinetic/pharmacodynamic model-guided identification of hypoxia-selective 1,2,4-benzotriazine 1,4-dioxides with antitumor activity: the role of extravascular transportMichael P Hay, Kevin O Hicks, Frederik B Pruijn, et al.
Cancer Research|January 28, 2004
Selective potentiation of the hypoxic cytotoxicity of tirapazamine by its 1-N-oxide metabolite SR 4317Bronwyn G Siim, Frederik B Pruijn, Joanna R Sturman, et al.
Journal of Medicinal Chemistry|May 16, 2003
Unsymmetrical DNA cross-linking agents: combination of the CBI and PBD pharmacophoresMoana Tercel, Stephen M Stribbling, Hilary Sheppard, et al.
Journal of Medicinal Chemistry|December 7, 2007
Hypoxia-selective 3-alkyl 1,2,4-benzotriazine 1,4-dioxides: the influence of hydrogen bond donors on extravascular transport and antitumor activityMichael P Hay, Karin Pchalek, Frederik B Pruijn, et al.
Bioorganic & Medicinal Chemistry Letters|October 12, 2010
Functionalized benzophenone, thiophene, pyridine, and fluorene thiosemicarbazone derivatives as inhibitors of cathepsin LG D Kishore Kumar, Gustavo E Chavarria, Amanda K Charlton-Sevcik, et al.
Pageof 2

Showing results (1-10 of 13) with videos related to

Sort By:
Pageof 2
Nature Reviews. Drug Discovery|October 4, 2003
HIF-1 as a target for drug developmentAmato Giaccia, Bronwyn G Siim, Randall S Johnson
Radiation Research|May 27, 2004
Oxygen dependence of the metabolic activation and cytotoxicity of tirapazamine: implications for extravascular transport and activity in tumorsKevin O Hicks, Bronwyn G Siim, Frederik B Pruijn, et al.
Journal of Natural Products|May 26, 2010
Regio- and stereospecific synthesis of mono-beta-d-glucuronic acid derivatives of combretastatin A-1Rajendra P Tanpure, Tracy E Strecker, David J Chaplin, et al.
Cancer Chemotherapy and Pharmacology|December 24, 2002
Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)Bronwyn G Siim, Alan E Lee, Sahar Shalal-Zwain, et al.
International Journal of Radiation Oncology, Biology, Physics|September 18, 2007
Oxygen dependence and extravascular transport of hypoxia-activated prodrugs: comparison of the dinitrobenzamide mustard PR-104A and tirapazamineKevin O Hicks, Hilary Myint, Adam V Patterson, et al.
Journal of Medicinal Chemistry|November 16, 2007
Pharmacokinetic/pharmacodynamic model-guided identification of hypoxia-selective 1,2,4-benzotriazine 1,4-dioxides with antitumor activity: the role of extravascular transportMichael P Hay, Kevin O Hicks, Frederik B Pruijn, et al.
Cancer Research|January 28, 2004
Selective potentiation of the hypoxic cytotoxicity of tirapazamine by its 1-N-oxide metabolite SR 4317Bronwyn G Siim, Frederik B Pruijn, Joanna R Sturman, et al.
Journal of Medicinal Chemistry|May 16, 2003
Unsymmetrical DNA cross-linking agents: combination of the CBI and PBD pharmacophoresMoana Tercel, Stephen M Stribbling, Hilary Sheppard, et al.
Journal of Medicinal Chemistry|December 7, 2007
Hypoxia-selective 3-alkyl 1,2,4-benzotriazine 1,4-dioxides: the influence of hydrogen bond donors on extravascular transport and antitumor activityMichael P Hay, Karin Pchalek, Frederik B Pruijn, et al.
Bioorganic & Medicinal Chemistry Letters|October 12, 2010
Functionalized benzophenone, thiophene, pyridine, and fluorene thiosemicarbazone derivatives as inhibitors of cathepsin LG D Kishore Kumar, Gustavo E Chavarria, Amanda K Charlton-Sevcik, et al.
Pageof 2