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Nature|September 26, 2009
An epistatic ratchet constrains the direction of glucocorticoid receptor evolutionJamie T Bridgham, Eric A Ortlund, Joseph W Thornton
Biorxiv : the Preprint Server for Biology|December 16, 2024
On the Analysis of Protein Genetic Architecture: Response to "Protein sequence landscapes are not so simple"Yeonwoo Park, Brian P H Metzger, Joseph W Thornton
Nature Communications|September 11, 2024
The simplicity of protein sequence-function relationshipsYeonwoo Park, Brian P H Metzger, Joseph W Thornton
Science (New York, N.Y.)|May 19, 2022
Epistatic drift causes gradual decay of predictability in protein evolutionYeonwoo Park, Brian P H Metzger, Joseph W Thornton
Nature|September 14, 2017
Alternative evolutionary histories in the sequence space of an ancient proteinTyler N Starr, Lora K Picton, Joseph W Thornton
Science (New York, N.Y.)|April 8, 2006
Evolution of hormone-receptor complexity by molecular exploitationJamie T Bridgham, Sean M Carroll, Joseph W Thornton
Molecular Biology and Evolution|September 19, 2008
Evolution of hormone signaling in elasmobranchs by exploitation of promiscuous receptorsSean Michael Carroll, Jamie T Bridgham, Joseph W Thornton
Plos Genetics|June 24, 2011
Mechanisms for the evolution of a derived function in the ancestral glucocorticoid receptorSean Michael Carroll, Eric A Ortlund, Joseph W Thornton
Current Opinion in Structural Biology|August 26, 2017
Evolution of protein specificity: insights from ancestral protein reconstructionMohammad A Siddiq, Georg Ka Hochberg, Joseph W Thornton
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