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The Journal of Clinical Investigation|June 1, 2026
Multimodal analysis of cell-free DNA identifies epigenetic biomarkers for amyotrophic lateral sclerosis diagnosis and progressionSebastian Michels, Chaorong Chen, Wolfgang P Ruf, et al.
Neuron|December 21, 2019
Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7Colleen A Stoyas, David D Bushart, Pawel M Switonski, et al.
Nature Neuroscience|April 15, 2020
Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72Qiang Zhu, Jie Jiang, Tania F Gendron, et al.
Annals of Neurology|November 4, 2014
Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerizationJudith Eschbach, Björn von Einem, Kathrin Müller, et al.
Biorxiv : the Preprint Server for Biology|August 8, 2025
Huntingtin preserves mitochondrial genome integrity in neurons, which is impaired in Huntington's diseaseSubrata Pradhan, Sagar Gaikwad, Chi-Lin Tsai, et al.
Nature Communications|May 9, 2013
A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseasesKyota Fujita, Yoko Nakamura, Tsutomu Oka, et al.
Science Translational Medicine|December 23, 2016
Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophyMaria Josè Polanco, Sara Parodi, Diana Piol, et al.
Cell Reports|November 12, 2023
Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative diseaseIan Matthews, Allison Birnbaum, Anastasia Gromova, et al.
Science Advances|January 6, 2023
Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of functionDiana Piol, Laura Tosatto, Emanuela Zuccaro, et al.
Science Translational Medicine|December 8, 2017
PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasisAudrey S Dickey, Dafne N Sanchez, Martin Arreola, et al.
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