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Acta Neuropathologica Communications|October 16, 2023
Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicityCraig L Bennett, Somasish Dastidar, Frederick J Arnold, et al.
The Journal of Biological Chemistry|November 20, 2008
Nutrient deprivation induces neuronal autophagy and implicates reduced insulin signaling in neuroprotective autophagy activationJessica E Young, Refugio A Martinez, Albert R La Spada
Science Translational Medicine|November 2, 2018
Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7Chenchen Niu, Thazah P Prakash, Aneeza Kim, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|February 21, 2009
Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/HrkJessica E Young, Gwenn A Garden, Refugio A Martinez, et al.
The Journal of Biological Chemistry|July 25, 2007
Proteolytic cleavage of ataxin-7 by caspase-7 modulates cellular toxicity and transcriptional dysregulationJessica E Young, Launce Gouw, Stephanie Propp, et al.
Nature Neuroscience|September 28, 2018
Converging pathways in neurodegeneration, from genetics to mechanismsLi Gan, Mark R Cookson, Leonard Petrucelli, et al.
Journal of Visualized Experiments : Jove|August 6, 2019
Low-Cost Gait Analysis for Behavioral Phenotyping of Mouse Models of Neuromuscular DiseaseVirginia Wertman, Anastasia Gromova, Albert R La Spada, et al.
Frontiers in Molecular Neuroscience|December 9, 2024
Increased nuclear import characterizes aberrant nucleocytoplasmic transport in neurons from patients with spinocerebellar ataxia type 7Joshua G Macopson-Jones, Maile Adams, Julien Philippe, et al.
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