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ACS Chemical Biology
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October 13, 2017
Discovery of a Distinct Chemical and Mechanistic Class of Allosteric HIV-1 Integrase Inhibitors with Antiretroviral Activity
Christine Burlein, Cheng Wang, Min Xu, et al.
Neurobiology of Disease
|
September 12, 2021
A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy
Mali Cosden, Sarah Jinn, Lihang Yao, et al.
ACS Medicinal Chemistry Letters
|
April 15, 2021
Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction
Douglas C Beshore, Gregory C Adam, Richard J O Barnard, et al.
Chemmedchem
|
January 29, 2011
Strategies towards improving the pharmacokinetic profile of ε-substituted lysinol-derived HIV protease inhibitors
Hemaka A Rajapakse, Abbas M Walji, Keith P Moore, et al.
Journal of Medicinal Chemistry
|
April 16, 2004
Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase
Anne B Eldrup, Charles R Allerson, C Frank Bennett, et al.
Journal of Medicinal Chemistry
|
December 4, 2003
Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithrombotics
James C Barrow, Philippe G Nantermet, Shaun R Stauffer, et al.
ACS Medicinal Chemistry Letters
|
August 14, 2024
Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure-Activity Relationships
Michael A Plotkin, Marc Labroli, Jeffrey Schubert, et al.
Antimicrobial Agents and Chemotherapy
|
May 23, 2012
MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants
Vincenzo Summa, Steven W Ludmerer, John A McCauley, et al.
ACS Medicinal Chemistry Letters
|
January 17, 2024
Fluorinated Isoindolinone-Based Glucosylceramide Synthase Inhibitors with Low Human Dose Projections
H Marie Loughran, Kathy M Schirripa, Anthony J Roecker, et al.
Journal of Medicinal Chemistry
|
October 1, 2004
Structure-activity relationship of heterobase-modified 2'-C-methyl ribonucleosides as inhibitors of hepatitis C virus RNA replication
Anne B Eldrup, Marija Prhavc, Jennifer Brooks, et al.
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Search research articles
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Showing results (61-70 of 78) with videos related to
Sort By:
Page
of 8
ACS Chemical Biology
|
October 13, 2017
Discovery of a Distinct Chemical and Mechanistic Class of Allosteric HIV-1 Integrase Inhibitors with Antiretroviral Activity
Christine Burlein, Cheng Wang, Min Xu, et al.
Neurobiology of Disease
|
September 12, 2021
A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy
Mali Cosden, Sarah Jinn, Lihang Yao, et al.
ACS Medicinal Chemistry Letters
|
April 15, 2021
Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction
Douglas C Beshore, Gregory C Adam, Richard J O Barnard, et al.
Chemmedchem
|
January 29, 2011
Strategies towards improving the pharmacokinetic profile of ε-substituted lysinol-derived HIV protease inhibitors
Hemaka A Rajapakse, Abbas M Walji, Keith P Moore, et al.
Journal of Medicinal Chemistry
|
April 16, 2004
Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase
Anne B Eldrup, Charles R Allerson, C Frank Bennett, et al.
Journal of Medicinal Chemistry
|
December 4, 2003
Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithrombotics
James C Barrow, Philippe G Nantermet, Shaun R Stauffer, et al.
ACS Medicinal Chemistry Letters
|
August 14, 2024
Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure-Activity Relationships
Michael A Plotkin, Marc Labroli, Jeffrey Schubert, et al.
Antimicrobial Agents and Chemotherapy
|
May 23, 2012
MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants
Vincenzo Summa, Steven W Ludmerer, John A McCauley, et al.
ACS Medicinal Chemistry Letters
|
January 17, 2024
Fluorinated Isoindolinone-Based Glucosylceramide Synthase Inhibitors with Low Human Dose Projections
H Marie Loughran, Kathy M Schirripa, Anthony J Roecker, et al.
Journal of Medicinal Chemistry
|
October 1, 2004
Structure-activity relationship of heterobase-modified 2'-C-methyl ribonucleosides as inhibitors of hepatitis C virus RNA replication
Anne B Eldrup, Marija Prhavc, Jennifer Brooks, et al.
Page
of 8