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Journal of Medicinal Chemistry
|
November 8, 2013
Aurora isoform selectivity: design and synthesis of imidazo[4,5-b]pyridine derivatives as highly selective inhibitors of Aurora-A kinase in cells
Vassilios Bavetsias, Amir Faisal, Simon Crumpler, et al.
Journal of Medicinal Chemistry
|
October 10, 2012
Optimization of imidazo[4,5-b]pyridine-based kinase inhibitors: identification of a dual FLT3/Aurora kinase inhibitor as an orally bioavailable preclinical development candidate for the treatment of acute myeloid leukemia
Vassilios Bavetsias, Simon Crumpler, Chongbo Sun, et al.
Journal of Medicinal Chemistry
|
June 23, 2010
Imidazo[4,5-b]pyridine derivatives as inhibitors of Aurora kinases: lead optimization studies toward the identification of an orally bioavailable preclinical development candidate
Vassilios Bavetsias, Jonathan M Large, Chongbo Sun, et al.
Epigenetics & Chromatin
|
March 8, 2017
Assessing histone demethylase inhibitors in cells: lessons learned
Stephanie B Hatch, Clarence Yapp, Raquel C Montenegro, et al.
Journal of Medicinal Chemistry
|
November 22, 2013
Structure-based design of orally bioavailable 1H-pyrrolo[3,2-c]pyridine inhibitors of mitotic kinase monopolar spindle 1 (MPS1)
Sébastien Naud, Isaac M Westwood, Amir Faisal, et al.
European Journal of Medicinal Chemistry
|
June 4, 2019
C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays
Yann-Vaï Le Bihan, Rachel M Lanigan, Butrus Atrash, et al.
Journal of Medicinal Chemistry
|
January 8, 2016
8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors
Vassilios Bavetsias, Rachel M Lanigan, Gian Filippo Ruda, et al.
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of 2
Search research articles
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Showing results (11-20 of 17) with videos related to
Sort By:
Page
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You have reached the last page of results.
This site can display upto 17 results.
Journal of Medicinal Chemistry
|
November 8, 2013
Aurora isoform selectivity: design and synthesis of imidazo[4,5-b]pyridine derivatives as highly selective inhibitors of Aurora-A kinase in cells
Vassilios Bavetsias, Amir Faisal, Simon Crumpler, et al.
Journal of Medicinal Chemistry
|
October 10, 2012
Optimization of imidazo[4,5-b]pyridine-based kinase inhibitors: identification of a dual FLT3/Aurora kinase inhibitor as an orally bioavailable preclinical development candidate for the treatment of acute myeloid leukemia
Vassilios Bavetsias, Simon Crumpler, Chongbo Sun, et al.
Journal of Medicinal Chemistry
|
June 23, 2010
Imidazo[4,5-b]pyridine derivatives as inhibitors of Aurora kinases: lead optimization studies toward the identification of an orally bioavailable preclinical development candidate
Vassilios Bavetsias, Jonathan M Large, Chongbo Sun, et al.
Epigenetics & Chromatin
|
March 8, 2017
Assessing histone demethylase inhibitors in cells: lessons learned
Stephanie B Hatch, Clarence Yapp, Raquel C Montenegro, et al.
Journal of Medicinal Chemistry
|
November 22, 2013
Structure-based design of orally bioavailable 1H-pyrrolo[3,2-c]pyridine inhibitors of mitotic kinase monopolar spindle 1 (MPS1)
Sébastien Naud, Isaac M Westwood, Amir Faisal, et al.
European Journal of Medicinal Chemistry
|
June 4, 2019
C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays
Yann-Vaï Le Bihan, Rachel M Lanigan, Butrus Atrash, et al.
Journal of Medicinal Chemistry
|
January 8, 2016
8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors
Vassilios Bavetsias, Rachel M Lanigan, Gian Filippo Ruda, et al.
Page
of 2