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The Journal of Biological Chemistry|August 16, 2017
Obesity and aging diminish sirtuin 1 (SIRT1)-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3Sanghoon Kwon, Sunmi Seok, Peter Yau, et al.
Elife|April 15, 2024
Hammerhead-type FXR agonists induce an enhancer RNA Fincor that ameliorates nonalcoholic steatohepatitis in miceJinjing Chen, Ruoyu Wang, Feng Xiong, et al.
Hepatology (Baltimore, Md.)|December 30, 2014
Farnesoid X receptor-induced lysine-specific histone demethylase reduces hepatic bile acid levels and protects the liver against bile acid toxicityYoung-Chae Kim, Sungsoon Fang, Sangwon Byun, et al.
Biorxiv : the Preprint Server for Biology|December 4, 2023
Hammerhead-type FXR agonists induce an eRNA FincoR that ameliorates nonalcoholic steatohepatitis in miceJinjing Chen, Ruoyu Wang, Feng Xiong, et al.
Archives of Biochemistry and Biophysics|October 24, 2007
Redundant enhancement of mouse constitutive androstane receptor transactivation by p160 coactivator family membersJun Xia, Lan Liao, Joy Sarkar, et al.
Genome Biology|December 5, 2015
Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2Young-Chae Kim, Sangwon Byun, Yang Zhang, et al.
Gastroenterology|December 7, 2018
Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol AbsorptionYoung-Chae Kim, Sangwon Byun, Sunmi Seok, et al.
The Journal of Biological Chemistry|June 22, 2023
Transgenic mice lacking FGF15/19-SHP phosphorylation display altered bile acids and gut bacteria, promoting nonalcoholic fatty liver diseaseYoung-Chae Kim, Ming Qi, Xingchen Dong, et al.
The EMBO Journal|June 10, 2022
Feeding activates FGF15-SHP-TFEB-mediated lipophagy in the gutSunmi Seok, Young-Chae Kim, Yang Zhang, et al.
Nature Communications|November 25, 2020
Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3AYoung-Chae Kim, Sunmi Seok, Yang Zhang, et al.
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