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Biochemistry|January 20, 1999
The crystal structure of human procathepsin KJ M LaLonde, B Zhao, C A Janson, et al.Journal of Medicinal Chemistry|August 1, 1997
Protein structure-based design, synthesis, and biological evaluation of 5-thia-2,6-diamino-4(3H)-oxopyrimidines: potent inhibitors of glycinamide ribonucleotide transformylase with potent cell growth inhibitionM D Varney, C L Palmer, W H Romines, et al.Journal of Medicinal Chemistry|May 26, 1995
Synthesis and biological evaluation of novel 2,6-diaminobenz[cd]indole inhibitors of thymidylate synthase using the protein structure as a guideM D Varney, C L Palmer, J G Deal, et al.Journal of Medicinal Chemistry|March 19, 1993
Design of thymidylate synthase inhibitors using protein crystal structures: the synthesis and biological evaluation of a novel class of 5-substituted quinazolinonesS E Webber, T M Bleckman, J Attard, et al.Cell|June 3, 1994
Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyproteinD A Matthews, W W Smith, R A Ferre, et al.Journal of Medicinal Chemistry|March 6, 1992
Design and synthesis of novel 6,7-imidazotetrahydroquinoline inhibitors of thymidylate synthase using iterative protein crystal structure analysisS H Reich, M A Fuhry, D Nguyen, et al.Biochemistry|December 31, 1997
Active site cavity of herpesvirus proteases revealed by the crystal structure of herpes simplex virus protease/inhibitor complexS S Hoog, W W Smith, X Qiu, et al.Biochemical and Biophysical Research Communications|March 29, 2000
Expression, purification, and crystallization of the Escherichia coli selenomethionyl beta-ketoacyl-acyl carrier protein synthase IIIS S Khandekar, A K Konstantinidis, C Silverman, et al.Biochemistry|April 12, 2000
Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitorN O Concha, C A Janson, P Rowling, et al.Journal of Medicinal Chemistry|November 7, 1998
Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsitesJ M LaLonde, B Zhao, W W Smith, et al.Pageof 5