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The Journal of Steroid Biochemistry and Molecular Biology|March 1, 1993
A detailed molecular model for human aromataseC A Laughton, M J Zvelebil, S NeidleBiochemical and Biophysical Research Communications|September 28, 1990
A molecular model for the enzyme cytochrome P450(17 alpha), a major target for the chemotherapy of prostatic cancerC A Laughton, S Neidle, M J Zvelebil, et al.Journal of Medicinal Chemistry|November 1, 1990
Inhibitors of the P450 enzymes aromatase and lyase. Crystallographic and molecular modeling studies suggest structural features of pyridylacetic acid derivatives responsible for differences in enzyme inhibitory activityC A Laughton, S NeidleNucleic Acids Research|December 25, 1992
Prediction of the structure of the Y+.R-.R(+)-type DNA triple helix by molecular modellingC A Laughton, S NeidleJournal of Molecular Biology|January 20, 1992
Molecular dynamics simulation of the DNA triplex d(TC)5.d(GA)5.d(C+T)5C A Laughton, S NeidleJournal of Medicinal Chemistry|July 24, 1992
A molecular modeling study of the interactions between the antiestrogen drug tamoxifen and several derivatives, and the calcium-binding protein calmodulinK J Edwards, C A Laughton, S NeidleActa Crystallographica. Section B, Structural Science|August 1, 1992
A note on the conformational flexibility of the antiestrogenic drug tamoxifen: preferred conformations in the free state and bound to the protein calmodulinK J Edwards, C A Laughton, S NeidleProtein Engineering|July 1, 1995
An approach to protein homology modelling based on an ensemble of NMR structures: application to the Sox-5 HMG-box proteinA A Adzhubei, C A Laughton, S NeidleAnti-Cancer Drug Design|March 1, 1997
Homology modelling of the enzyme P450 17 alpha-hydroxylase/17,20-lyase--a target for prostate cancer chemotherapy--from the crystal structure of P450BM-3D F Burke, C A Laughton, S NeidleJournal of Biomolecular Structure & Dynamics|October 1, 1990
Molecular-mechanics modelling of drug-DNA structures; the effects of differing dielectric treatment on helix parameters and comparison with a fully solvated structural modelM Orozco, C A Laughton, P Herzyk, et al.Pageof 22