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Journal of Medicinal Chemistry
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September 25, 2008
Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretase
James C Barrow, Shaun R Stauffer, Kenneth E Rittle, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 24, 2010
SAR of tertiary carbinamine derived BACE1 inhibitors: role of aspartate ligand amine pKa in enzyme inhibition
Hemaka A Rajapakse, Philippe G Nantermet, Harold G Selnick, et al.
Cell Biochemistry and Biophysics
|
July 8, 2009
Positive allosteric interaction of structurally diverse T-type calcium channel antagonists
Victor N Uebele, Cindy E Nuss, Steven V Fox, et al.
ACS Chemical Neuroscience
|
August 4, 2012
Characterization of non-nitrocatechol pan and isoform specific catechol-O-methyltransferase inhibitors and substrates
Ronald G Robinson, Sean M Smith, Scott E Wolkenberg, et al.
Journal of Medicinal Chemistry
|
May 28, 2004
Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors
Mary Beth Young, James C Barrow, Kristen L Glass, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Short-acting T-type calcium channel antagonists significantly modify sleep architecture in rodents
Zhi-Qiang Yang, Kelly-Ann S Schlegel, Youheng Shu, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 22, 2015
Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potency
Melissa Egbertson, Georgia B McGaughey, Steven M Pitzenberger, et al.
Journal of Medicinal Chemistry
|
June 11, 2008
Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonist
William D Shipe, James C Barrow, Zhi-Qiang Yang, et al.
Journal of Medicinal Chemistry
|
September 27, 2008
Discovery of 1,4-substituted piperidines as potent and selective inhibitors of T-type calcium channels
Zhi-Qiang Yang, James C Barrow, William D Shipe, et al.
Journal of Medicinal Chemistry
|
February 7, 2003
Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines
Christopher S Burgey, Kyle A Robinson, Terry A Lyle, et al.
Page
of 14
Search research articles
Search
Showing results (121-130 of 131) with videos related to
Sort By:
Page
of 14
Journal of Medicinal Chemistry
|
September 25, 2008
Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretase
James C Barrow, Shaun R Stauffer, Kenneth E Rittle, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 24, 2010
SAR of tertiary carbinamine derived BACE1 inhibitors: role of aspartate ligand amine pKa in enzyme inhibition
Hemaka A Rajapakse, Philippe G Nantermet, Harold G Selnick, et al.
Cell Biochemistry and Biophysics
|
July 8, 2009
Positive allosteric interaction of structurally diverse T-type calcium channel antagonists
Victor N Uebele, Cindy E Nuss, Steven V Fox, et al.
ACS Chemical Neuroscience
|
August 4, 2012
Characterization of non-nitrocatechol pan and isoform specific catechol-O-methyltransferase inhibitors and substrates
Ronald G Robinson, Sean M Smith, Scott E Wolkenberg, et al.
Journal of Medicinal Chemistry
|
May 28, 2004
Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors
Mary Beth Young, James C Barrow, Kristen L Glass, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Short-acting T-type calcium channel antagonists significantly modify sleep architecture in rodents
Zhi-Qiang Yang, Kelly-Ann S Schlegel, Youheng Shu, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 22, 2015
Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potency
Melissa Egbertson, Georgia B McGaughey, Steven M Pitzenberger, et al.
Journal of Medicinal Chemistry
|
June 11, 2008
Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonist
William D Shipe, James C Barrow, Zhi-Qiang Yang, et al.
Journal of Medicinal Chemistry
|
September 27, 2008
Discovery of 1,4-substituted piperidines as potent and selective inhibitors of T-type calcium channels
Zhi-Qiang Yang, James C Barrow, William D Shipe, et al.
Journal of Medicinal Chemistry
|
February 7, 2003
Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines
Christopher S Burgey, Kyle A Robinson, Terry A Lyle, et al.
Page
of 14