Search research articles
Contact Us
Filters
Showing results (31-40 of 41) with videos related to
Page
of 5
Sort By:
RSC Medicinal Chemistry
|
December 22, 2022
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates
S Paul Jones, James D Firth, Mary C Wheldon, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
December 26, 2019
Cellular Target Engagement Approaches to Monitor Epigenetic Reader Domain Interactions
Alexander N Phillipou, Charles S Lay, Charlotte E Carver, et al.
Journal of Medicinal Chemistry
|
July 14, 2021
Optimization of a Series of 2,3-Dihydrobenzofurans as Highly Potent, Second Bromodomain (BD2)-Selective, Bromo and Extra-Terminal Domain (BET) Inhibitors
Simon C C Lucas, Stephen J Atkinson, Chun-Wa Chung, et al.
Journal of Medicinal Chemistry
|
March 21, 2024
Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders
Simon C C Lucas, Afshan Ahmed, S Neha Ashraf, et al.
Journal of Medicinal Chemistry
|
August 10, 2019
A Qualified Success: Discovery of a New Series of ATAD2 Bromodomain Inhibitors with a Novel Binding Mode Using High-Throughput Screening and Hit Qualification
Paul Bamborough, Chun-Wa Chung, Emmanuel H Demont, et al.
Journal of Medicinal Chemistry
|
June 25, 2024
Design of a Lead-Like Cysteine-Targeting Covalent Library and the Identification of Hits to Cys55 of Bfl-1
Simon C C Lucas, Alexander G Milbradt, J Henry Blackwell, et al.
Journal of Medicinal Chemistry
|
September 18, 2024
Structure-Based Optimization of a Series of Covalent, Cell Active Bfl-1 Inhibitors
Simon C C Lucas, J Henry Blackwell, Ulf Börjesson, et al.
ACS Medicinal Chemistry Letters
|
August 20, 2025
Discovery of Small-Molecule Ligands for the E3 Ligase STUB1/CHIP from a DNA-Encoded Library Screen
Simon C C Lucas, Alexander G Milbradt, Jason Breed, et al.
Journal of Medicinal Chemistry
|
December 23, 2025
Optimization and Chemoproteomic Profiling of a Selective, Covalent Bfl-1-Targeting Cellular Tool
J Henry Blackwell, Simon C C Lucas, Giovanni Battocchio, et al.
ACS Medicinal Chemistry Letters
|
June 19, 2024
Identification and Evaluation of Reversible Covalent Binders to Cys55 of Bfl-1 from a DNA-Encoded Chemical Library Screen
Simon C C Lucas, J Henry Blackwell, Ulf Börjesson, et al.
Page
of 5
Search research articles
Search
Showing results (31-40 of 41) with videos related to
Sort By:
Page
of 5
RSC Medicinal Chemistry
|
December 22, 2022
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates
S Paul Jones, James D Firth, Mary C Wheldon, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
December 26, 2019
Cellular Target Engagement Approaches to Monitor Epigenetic Reader Domain Interactions
Alexander N Phillipou, Charles S Lay, Charlotte E Carver, et al.
Journal of Medicinal Chemistry
|
July 14, 2021
Optimization of a Series of 2,3-Dihydrobenzofurans as Highly Potent, Second Bromodomain (BD2)-Selective, Bromo and Extra-Terminal Domain (BET) Inhibitors
Simon C C Lucas, Stephen J Atkinson, Chun-Wa Chung, et al.
Journal of Medicinal Chemistry
|
March 21, 2024
Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders
Simon C C Lucas, Afshan Ahmed, S Neha Ashraf, et al.
Journal of Medicinal Chemistry
|
August 10, 2019
A Qualified Success: Discovery of a New Series of ATAD2 Bromodomain Inhibitors with a Novel Binding Mode Using High-Throughput Screening and Hit Qualification
Paul Bamborough, Chun-Wa Chung, Emmanuel H Demont, et al.
Journal of Medicinal Chemistry
|
June 25, 2024
Design of a Lead-Like Cysteine-Targeting Covalent Library and the Identification of Hits to Cys55 of Bfl-1
Simon C C Lucas, Alexander G Milbradt, J Henry Blackwell, et al.
Journal of Medicinal Chemistry
|
September 18, 2024
Structure-Based Optimization of a Series of Covalent, Cell Active Bfl-1 Inhibitors
Simon C C Lucas, J Henry Blackwell, Ulf Börjesson, et al.
ACS Medicinal Chemistry Letters
|
August 20, 2025
Discovery of Small-Molecule Ligands for the E3 Ligase STUB1/CHIP from a DNA-Encoded Library Screen
Simon C C Lucas, Alexander G Milbradt, Jason Breed, et al.
Journal of Medicinal Chemistry
|
December 23, 2025
Optimization and Chemoproteomic Profiling of a Selective, Covalent Bfl-1-Targeting Cellular Tool
J Henry Blackwell, Simon C C Lucas, Giovanni Battocchio, et al.
ACS Medicinal Chemistry Letters
|
June 19, 2024
Identification and Evaluation of Reversible Covalent Binders to Cys55 of Bfl-1 from a DNA-Encoded Chemical Library Screen
Simon C C Lucas, J Henry Blackwell, Ulf Börjesson, et al.
Page
of 5