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JIMD Reports|August 8, 2025
Farber's Lipogranulomatosis: Multimodal Therapy With Tocilizumab and Consolidative HSCT Improves Assessment, and Long-Term OutcomeNathanael C C Lucas, Claire Horgan, Omima Mustafa, et al.
ACS Medicinal Chemistry Letters|April 16, 2025
Discovery of a Series of Covalent Ligands That Bind to Cys77 of the Von Hippel-Lindau Tumor Suppressor Protein (VHL)Simon C C Lucas, Yong Xu, Sarah Hewitt, et al.
Public Health|July 16, 2023
Institutional outbreaks of influenza-like illnesses in the state of São Paulo: an analysis of the epidemiological profile during the COVID-19 pandemicP C C Lucas, C Lorenz, G L Florez-Montero, et al.
Journal of the American Chemical Society|July 30, 2025
Modular Synthetic Platform for the Elaboration of Fragments in Three Dimensions for Fragment-Based Drug DiscoveryAndres R Gomez-Angel, Hanna F Klein, Stephen Y Yao, et al.
Journal of Medicinal Chemistry|April 24, 2020
Optimization of Potent ATAD2 and CECR2 Bromodomain Inhibitors with an Atypical Binding ModeSimon C C Lucas, Stephen J Atkinson, Paul Bamborough, et al.
RSC Medicinal Chemistry|November 3, 2022
Fragment screening at AstraZeneca: developing the next generation biophysics fragment setSimon C C Lucas, Ulf Börjesson, Mark J Bostock, et al.
ACS Medicinal Chemistry Letters|June 18, 2025
Discovery of Pyrimidoindolones as Novel Family VIII Bromodomain BindersJeffrey A Boerth, Marianne Schimpl, Simon C C Lucas, et al.
RSC Medicinal Chemistry|December 22, 2022
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinatesS Paul Jones, James D Firth, Mary C Wheldon, et al.
Journal of Medicinal Chemistry|July 13, 2026
X-ray Crystallography-Guided Design and Synthesis of Cyclopentyl Heteroaryl Carboxylic Acid-Based Inhibitors of the SARS-CoV-2 Nsp3 Macrodomain (Mac1)Xinyu Wang, William T W Butler, James R Donald, et al.
SLAS Discovery : Advancing Life Sciences R & D|December 26, 2019
Cellular Target Engagement Approaches to Monitor Epigenetic Reader Domain InteractionsAlexander N Phillipou, Charles S Lay, Charlotte E Carver, et al.
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