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The Journal of Biological Chemistry|January 31, 1998
Identification of amino acids contributing to high and low affinity d-tubocurarine sites in the Torpedo nicotinic acetylcholine receptorD C Chiara, J B Cohen
Molecular Pharmacology|January 26, 2002
Mapping the agonist binding site of the nicotinic acetylcholine receptor by cysteine scanning mutagenesis: antagonist footprint and secondary structure predictionDeirdre Sullivan, David C Chiara, Jonathan B Cohen
Biochemistry|June 3, 1999
Structure of the agonist-binding sites of the Torpedo nicotinic acetylcholine receptor: affinity-labeling and mutational analyses identify gamma Tyr-111/delta Arg-113 as antagonist affinity determinantsD C Chiara, Y Xie, J B Cohen
Molecular Pharmacology|May 17, 2001
Interactions between 3-(Trifluoromethyl)-3-(m-[(125)I]iodophenyl)diazirine and tetracaine, phencyclidine, or histrionicotoxin in the Torpedo series nicotinic acetylcholine receptor ion channelM J Gallagher, D C Chiara, J B Cohen
Biochemistry|August 31, 2006
Mapping the structural requirements for nicotinic acetylcholine receptor activation by using tethered alkyltrimethylammonium agonists and antagonistsDeirdre S Stewart, David C Chiara, Jonathan B Cohen
FEBS Letters|March 25, 1998
Identification of tryptophan 55 as the primary site of [3H]nicotine photoincorporation in the gamma-subunit of the Torpedo nicotinic acetylcholine receptorD C Chiara, R E Middleton, J B Cohen
Neuropharmacology|October 16, 2014
Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptorsStuart A Forman, David C Chiara, Keith W Miller
The Journal of Biological Chemistry|July 13, 2000
Probing the structure of the nicotinic acetylcholine receptor with 4-benzoylbenzoylcholine, a novel photoaffinity competitive antagonistD Wang, D C Chiara, Y Xie, et al.
Methods in Molecular Biology (Clifton, N.J.)|May 17, 2017
Photoaffinity Labeling of Pentameric Ligand-Gated Ion Channels: A Proteomic Approach to Identify Allosteric Modulator Binding SitesSelwyn S Jayakar, Gordon Ang, David C Chiara, et al.
The Journal of Biological Chemistry|January 20, 2010
Numerous classes of general anesthetics inhibit etomidate binding to gamma-aminobutyric acid type A (GABAA) receptorsGuo-Dong Li, David C Chiara, Jonathan B Cohen, et al.
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