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Journal of Medicinal Chemistry
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February 7, 2024
Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2
Joshua R Hummel, Kai-Jiong Xiao, Jeffrey C Yang, et al.
Immunity
|
April 13, 2016
Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor
Leopold Kong, Bin Ju, Yajing Chen, et al.
Journal of Medicinal Chemistry
|
November 10, 2022
Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3
Artem Shvartsbart, Jeremy J Roach, Michael R Witten, et al.
Journal of Medicinal Chemistry
|
May 27, 2026
Discovery of the Orally Bioavailable Isoform Selective Janus Kinase 1 (JAK1) Compound Povorcitinib (INCB054707) for the Treatment of Inflammatory and Autoimmune Diseases
Jincong Zhuo, Yun-Long Li, Ding-Quan Qian, et al.
Nature Structural & Molecular Biology
|
May 28, 2013
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
Leopold Kong, Jeong Hyun Lee, Katie J Doores, et al.
Journal of Medicinal Chemistry
|
January 8, 2025
Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor
Qinda Ye, Artem Shvartsbart, Zhenwu Li, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
October 15, 2010
The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role
S Sri Krishna, L Aravind, Constantina Bakolitsa, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
October 15, 2010
Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation
Mitchell D Miller, L Aravind, Constantina Bakolitsa, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
October 15, 2010
Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism
Hsiu Ju Chiu, Constantina Bakolitsa, Arne Skerra, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
October 15, 2010
The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes
Hsiu Ju Chiu, Polat Abdubek, Tamara Astakhova, et al.
Page
of 9
Search research articles
Search
Showing results (51-60 of 88) with videos related to
Sort By:
Page
of 9
Journal of Medicinal Chemistry
|
February 7, 2024
Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2
Joshua R Hummel, Kai-Jiong Xiao, Jeffrey C Yang, et al.
Immunity
|
April 13, 2016
Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor
Leopold Kong, Bin Ju, Yajing Chen, et al.
Journal of Medicinal Chemistry
|
November 10, 2022
Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3
Artem Shvartsbart, Jeremy J Roach, Michael R Witten, et al.
Journal of Medicinal Chemistry
|
May 27, 2026
Discovery of the Orally Bioavailable Isoform Selective Janus Kinase 1 (JAK1) Compound Povorcitinib (INCB054707) for the Treatment of Inflammatory and Autoimmune Diseases
Jincong Zhuo, Yun-Long Li, Ding-Quan Qian, et al.
Nature Structural & Molecular Biology
|
May 28, 2013
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
Leopold Kong, Jeong Hyun Lee, Katie J Doores, et al.
Journal of Medicinal Chemistry
|
January 8, 2025
Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor
Qinda Ye, Artem Shvartsbart, Zhenwu Li, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
October 15, 2010
The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role
S Sri Krishna, L Aravind, Constantina Bakolitsa, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
October 15, 2010
Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation
Mitchell D Miller, L Aravind, Constantina Bakolitsa, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
October 15, 2010
Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism
Hsiu Ju Chiu, Constantina Bakolitsa, Arne Skerra, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
October 15, 2010
The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes
Hsiu Ju Chiu, Polat Abdubek, Tamara Astakhova, et al.
Page
of 9