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ACS Chemical Biology|April 18, 2020
Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site CysteineCharlene Bashore, Priyadarshini Jaishankar, Nicholas J Skelton, et al.
The Journal of Biological Chemistry|September 13, 2018
Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9Michael J Holliday, Ryan Ferrao, Gladys de Leon Boenig, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 25, 2016
GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranesRobin A Aglietti, Alberto Estevez, Aaron Gupta, et al.
Nature Communications|July 13, 2019
Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activationMichael J Holliday, Axel Witt, Alejandro Rodríguez Gama, et al.
Nature Structural & Molecular Biology|November 11, 2014
Internal motions prime cIAP1 for rapid activationAaron H Phillips, Allyn J Schoeffler, Tsutomu Matsui, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 24, 2012
Molecular basis of Tank-binding kinase 1 activation by transautophosphorylationXiaolei Ma, Elizabeth Helgason, Qui T Phung, et al.
Structure (London, England : 1993)|February 21, 2025
Discovery and characterization of potent macrocycle inhibitors of ubiquitin-specific protease-7Rafael Miranda, Francesca Anson, Shannon T Smith, et al.
The EMBO Journal|November 30, 2010
c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signallingJasmin N Dynek, Tatiana Goncharov, Erin C Dueber, et al.
Current Oncology (Toronto, Ont.)|April 25, 2025
Folliculin (FLCN) in Thyroid Tumors: Incidence, Significance, and Role as a Driver Gene and Secondary AlterationFaisal A Hassan, Camryn Slone, Robert J McDonald, et al.
Journal of Medicinal Chemistry|March 29, 2011
Identification, characterization, and implications of species-dependent plasma protein binding for the oral Hedgehog pathway inhibitor vismodegib (GDC-0449)Anthony M Giannetti, Harvey Wong, Gerrit J P Dijkgraaf, et al.
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