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Molecular and Cellular Biology|November 1, 1993
Insulin-stimulated oocyte maturation requires insulin receptor substrate 1 and interaction with the SH2 domains of phosphatidylinositol 3-kinaseL M Chuang, M G Myers, J M Backer, et al.
The Journal of Biological Chemistry|May 25, 1993
Insulin stimulates serine and tyrosine phosphorylation in the juxtamembrane region of the insulin receptorE P Feener, J M Backer, G L King, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 11, 1992
IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85M G Myers, J M Backer, X J Sun, et al.
The Journal of Cell Biology|August 1, 1992
The insulin receptor juxtamembrane region contains two independent tyrosine/beta-turn internalization signalsJ M Backer, S E Shoelson, M A Weiss, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 13, 1997
Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinaseA G Ryazanov, M D Ward, C E Mendola, et al.
Nature|July 4, 1991
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction proteinX J Sun, P Rothenberg, C R Kahn, et al.
The EMBO Journal|September 11, 1992
Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulationJ M Backer, M G Myers, S E Shoelson, et al.
The Journal of Cell Biology|October 3, 2001
Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturationO V Vieira, R J Botelho, L Rameh, et al.
The EMBO Journal|May 1, 1993
The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signallingE Y Skolnik, C H Lee, A Batzer, et al.
Oncogene|July 5, 2011
Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasisT Smirnova, Z N Zhou, R J Flinn, et al.
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