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Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 30, 2015
In Vitro Kinetic Characterization of Axitinib MetabolismMichael A Zientek, Theunis C Goosen, Elaine Tseng, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 9, 2013
Quantitative prediction of repaglinide-rifampicin complex drug interactions using dynamic and static mechanistic models: delineating differential CYP3A4 induction and OATP1B1 inhibition potential of rifampicinManthena V S Varma, Jian Lin, Yi-An Bi, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 9, 2018
6-Chloro-5-[4-(1-Hydroxycyclobutyl)Phenyl]-1H-Indole-3-Carboxylic Acid is a Highly Selective Substrate for Glucuronidation by UGT1A1, Relative to β-EstradiolKimberly Lapham, Jian Lin, Jonathan Novak, et al.Chemical Research in Toxicology|September 20, 2012
Insights into the novel hydrolytic mechanism of a diethyl 2-phenyl-2-(2-arylacetoxy)methyl malonate ester-based microsomal triglyceride transfer protein (MTP) inhibitorTim Ryder, Gregory S Walker, Theunis C Goosen, et al.Clinical Pharmacology and Therapeutics|December 14, 2004
Bergamottin contribution to the grapefruit juice-felodipine interaction and disposition in humansTheunis C Goosen, Doré Cillié, David G Bailey, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 31, 2012
Selective mechanism-based inactivation of CYP3A4 by CYP3cide (PF-04981517) and its utility as an in vitro tool for delineating the relative roles of CYP3A4 versus CYP3A5 in the metabolism of drugsRobert L Walsky, R Scott Obach, Ruth Hyland, et al.British Journal of Haematology|September 1, 1980
Quantitative aspects of the destruction of red cells sensitized with IgG1 autoantibodies: an application of flow cytofluorometryF W van der Meulen, H G de Bruin, P C Goosen, et al.Gut|March 13, 2003
Hepatic osteodystrophy in rats results mainly from portasystemic shuntingS W van der Merwe, J B van den Bogaerde, C Goosen, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 27, 2009
In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studiesLifei Wang, Donglu Zhang, Nirmala Raghavan, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 22, 2014
Metabolites in safety testing assessment in early clinical development: a case study with a glucokinase activatorRaman Sharma, John Litchfield, Karen Atkinson, et al.Pageof 9