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Journal of Medicinal Chemistry|March 22, 2021
Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron MicroscopyJack A Terrett, Huifen Chen, Daniel G Shore, et al.Journal of Medicinal Chemistry|June 16, 2012
Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2Mark Zak, Rohan Mendonca, Mercedesz Balazs, et al.Journal of Medicinal Chemistry|May 11, 2013
Identification of C-2 hydroxyethyl imidazopyrrolopyridines as potent JAK1 inhibitors with favorable physicochemical properties and high selectivity over JAK2Mark Zak, Christopher A Hurley, Stuart I Ward, et al.Pageof 37