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International Journal of Pharmaceutics|December 22, 2023
Coadministration of ABCB1/P-glycoprotein inhibitor elacridar improves tissue distribution of ritonavir-boosted oral cabazitaxel in miceNancy H C Loos, Margarida L F Martins, Daniëlle de Jong, et al.
Molecular Pharmaceutics|February 29, 2024
Interplay of Ritonavir-Boosted Oral Cabazitaxel with the Organic Anion-Transporting Polypeptide (OATP) Uptake Transporters and Carboxylesterase 1 in MiceNancy H C Loos, Margarida L Ferreira Martins, Jamie Rijmers, et al.
Transplantation Proceedings|December 20, 2007
Relationship between procalcitonin values and infection in brain-dead organ donorsO Rangeard, G Audibert, J-F Perrier, et al.
Pharmacological Research|February 22, 2022
ABCB1 limits brain exposure of the KRASG12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availabilityNancy H C Loos, Irene A Retmana, Wenlong Li, et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|August 16, 2023
Pharmacokinetics of the KRASG12C inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1cNancy H C Loos, Irene A Retmana, Jamie Rijmers, et al.
Molecular Pharmaceutics|September 23, 2024
Brain Exposure to the Macrocyclic ALK Inhibitor Zotizalkib is Restricted by ABCB1, and Its Plasma Disposition is Affected by Mouse Carboxylesterase 1cJamie Rijmers, Rolf W Sparidans, Manon Acda, et al.
Molecular Pharmaceutics|November 3, 2021
P-Glycoprotein (ABCB1/MDR1) Controls Brain Penetration and Intestinal Disposition of the PARP1/2 Inhibitor NiraparibMargarida L F Martins, Nancy H C Loos, Sümeyra Mucuk, et al.
Pharmaceutical Research|June 21, 2023
P-glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Main Active Heroin Metabolites 6-monoacetylmorphine (6-MAM) and Morphine in MiceMargarida L F Martins, Nancy H C Loos, Malika El Yattouti, et al.
Ergonomics|May 25, 2010
Validity of estimates of spinal compression forces obtained from worksite measurementsJaap H van Dieën, Gert S Faber, Romy C C Loos, et al.
Nucleosides, Nucleotides & Nucleic Acids|September 21, 2001
The design and synthesis of purine inhibitors of CDK2. IIIP W Shum, N P Peet, P M Weintraub, et al.
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