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C M Vaidya

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Biochemical Pharmacology|May 16, 2000
Efficient utilization of the reduced folate carrier in CCRF-CEM human leukemic lymphoblasts by the potent antifolate N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L- ornithine (PT523) and its B-ring analoguesJ E Wright, C M Vaidya, Y Chen, et al.
Pharmacology & Therapeutics|March 31, 2000
The effect of side-chain, para-aminobenzoyl region, and B-ring modifications on dihydrofolate reductase binding, influx via the reduced folate carrier, and cytotoxicity of the potent nonpolyglutamatable antifolate N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L- ornithineA Rosowsky, J E Wright, C M Vaidya, et al.
Journal of Medicinal Chemistry|January 31, 1997
Analogues of N alpha-(4-amino-4-deoxypteroyl)-N delta-hemiphthaloyl-L-ornithine (PT523) modified in the side chain: synthesis and biological evaluationA Rosowsky, C M Vaidya, H Bader, et al.
Journal of Medicinal Chemistry|April 26, 2000
Analogues of the potent nonpolyglutamatable antifolate N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L-ornithine (PT523) with modifications in the side chain, p-aminobenzoyl moiety, or 9,10-bridge: synthesis and in vitro antitumor activityA Rosowsky, J E Wright, C M Vaidya, et al.
Journal of Medicinal Chemistry|December 19, 1998
Synthesis and potent antifolate activity and cytotoxicity of B-ring deaza analogues of the nonpolyglutamatable dihydrofolate reductase inhibitor Nalpha-(4-amino-4-deoxypteroyl)-Ndelta-hemiphthaloyl- L-ornithine (PT523)A Rosowsky, J E Wright, C M Vaidya, et al.
Pageof 1

Showing results (1-10 of 5) with videos related to

Sort By:
Pageof 1
Biochemical Pharmacology|May 16, 2000
Efficient utilization of the reduced folate carrier in CCRF-CEM human leukemic lymphoblasts by the potent antifolate N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L- ornithine (PT523) and its B-ring analoguesJ E Wright, C M Vaidya, Y Chen, et al.
Pharmacology & Therapeutics|March 31, 2000
The effect of side-chain, para-aminobenzoyl region, and B-ring modifications on dihydrofolate reductase binding, influx via the reduced folate carrier, and cytotoxicity of the potent nonpolyglutamatable antifolate N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L- ornithineA Rosowsky, J E Wright, C M Vaidya, et al.
Journal of Medicinal Chemistry|January 31, 1997
Analogues of N alpha-(4-amino-4-deoxypteroyl)-N delta-hemiphthaloyl-L-ornithine (PT523) modified in the side chain: synthesis and biological evaluationA Rosowsky, C M Vaidya, H Bader, et al.
Journal of Medicinal Chemistry|April 26, 2000
Analogues of the potent nonpolyglutamatable antifolate N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L-ornithine (PT523) with modifications in the side chain, p-aminobenzoyl moiety, or 9,10-bridge: synthesis and in vitro antitumor activityA Rosowsky, J E Wright, C M Vaidya, et al.
Journal of Medicinal Chemistry|December 19, 1998
Synthesis and potent antifolate activity and cytotoxicity of B-ring deaza analogues of the nonpolyglutamatable dihydrofolate reductase inhibitor Nalpha-(4-amino-4-deoxypteroyl)-Ndelta-hemiphthaloyl- L-ornithine (PT523)A Rosowsky, J E Wright, C M Vaidya, et al.
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