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C Magliaro

Showing results (11-20 of 19) with videos related to

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International Journal of Molecular Sciences|January 25, 2025
An Immunocytochemistry Method to Investigate the Translationally Active HIV ReservoirGuoxin Wu, Samuel H Keller, Ryan T Walters, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 ReceptorRobert M Garbaccio, Edward J Brnardic, Mark E Fraley, et al.
Bioorganic & Medicinal Chemistry Letters|January 27, 2016
Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosisMark E Layton, Alexander J Reif, Timothy J Hartingh, et al.
Bioorganic & Medicinal Chemistry Letters|April 23, 2010
3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead effortsEdward J Brnardic, Mark E Fraley, Robert M Garbaccio, et al.
ACS Medicinal Chemistry Letters|March 18, 2016
Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDIJoseph E Pero, Michael A Rossi, Michael J Kelly, et al.
ACS Chemical Biology|December 30, 2016
Iterative Focused Screening with Biological Fingerprints Identifies Selective Asc-1 Inhibitors Distinct from Traditional High Throughput ScreeningPeter S Kutchukian, Lee Warren, Brian C Magliaro, et al.
Neuropharmacology|January 8, 2013
Mechanism based neurotoxicity of mGlu5 positive allosteric modulators--development challenges for a promising novel antipsychotic targetSophie Parmentier-Batteur, Peter H Hutson, Karsten Menzel, et al.
Neuropharmacology|May 31, 2011
The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodentsP H Hutson, E N Finger, B C Magliaro, et al.
Journal of Medicinal Chemistry|February 27, 2020
Discovery of [<sup>11</sup>C]MK-6884: A Positron Emission Tomography (PET) Imaging Agent for the Study of M4Muscarinic Receptor Positive Allosteric Modulators (PAMs) in Neurodegenerative DiseasesLing Tong, Wenping Li, Michael Man-Chu Lo, et al.
Pageof 2

Showing results (11-20 of 19) with videos related to

Sort By:
Pageof 2
You have reached the last page of results.This site can display upto 19 results.
International Journal of Molecular Sciences|January 25, 2025
An Immunocytochemistry Method to Investigate the Translationally Active HIV ReservoirGuoxin Wu, Samuel H Keller, Ryan T Walters, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 ReceptorRobert M Garbaccio, Edward J Brnardic, Mark E Fraley, et al.
Bioorganic & Medicinal Chemistry Letters|January 27, 2016
Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosisMark E Layton, Alexander J Reif, Timothy J Hartingh, et al.
Bioorganic & Medicinal Chemistry Letters|April 23, 2010
3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead effortsEdward J Brnardic, Mark E Fraley, Robert M Garbaccio, et al.
ACS Medicinal Chemistry Letters|March 18, 2016
Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDIJoseph E Pero, Michael A Rossi, Michael J Kelly, et al.
ACS Chemical Biology|December 30, 2016
Iterative Focused Screening with Biological Fingerprints Identifies Selective Asc-1 Inhibitors Distinct from Traditional High Throughput ScreeningPeter S Kutchukian, Lee Warren, Brian C Magliaro, et al.
Neuropharmacology|January 8, 2013
Mechanism based neurotoxicity of mGlu5 positive allosteric modulators--development challenges for a promising novel antipsychotic targetSophie Parmentier-Batteur, Peter H Hutson, Karsten Menzel, et al.
Neuropharmacology|May 31, 2011
The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodentsP H Hutson, E N Finger, B C Magliaro, et al.
Journal of Medicinal Chemistry|February 27, 2020
Discovery of [<sup>11</sup>C]MK-6884: A Positron Emission Tomography (PET) Imaging Agent for the Study of M4Muscarinic Receptor Positive Allosteric Modulators (PAMs) in Neurodegenerative DiseasesLing Tong, Wenping Li, Michael Man-Chu Lo, et al.
Pageof 2