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Journal of Medicinal Chemistry
|
January 11, 2008
Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor
Gang Zhao, Andrew J Souers, Martin Voorbach, et al.
Bioorganic & Medicinal Chemistry
|
May 27, 2008
Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain
Irene Drizin, Robert J Gregg, Marc J C Scanio, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 26, 2006
Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: the effects of chirality on substituted indan-1-ylamines
Andrew J Souers, Rajesh R Iyengar, Andrew S Judd, et al.
Journal of Medicinal Chemistry
|
October 27, 2006
Optimization of chromone-2-carboxamide melanin concentrating hormone receptor 1 antagonists: assessment of potency, efficacy, and cardiovascular safety
John K Lynch, Jennifer C Freeman, Andrew S Judd, et al.
International Journal for Parasitology
|
April 1, 2020
Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned
Ryan Choi, Matthew A Hulverson, Wenlin Huang, et al.
Journal of Medicinal Chemistry
|
January 8, 2008
Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain
Michael E Kort, Irene Drizin, Robert J Gregg, et al.
Journal of Medicinal Chemistry
|
December 8, 2006
Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction
Meena V Patel, Teodozyj Kolasa, Kathleen Mortell, et al.
Journal of Medicinal Chemistry
|
January 24, 2012
Identification and preliminary characterization of a potent, safe, and orally efficacious inhibitor of acyl-CoA:diacylglycerol acyltransferase 1
Vince S C Yeh, David W A Beno, Sevan Brodjian, et al.
Molecular Cancer Therapeutics
|
March 31, 2021
Expanding the Repertoire for "Large Small Molecules": Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers
Ahmed Hamed Salem, Zhi-Fu Tao, Orlando F Bueno, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
May 3, 2007
ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models
Cherrie K Donawho, Yan Luo, Yanping Luo, et al.
Page
of 66
Search research articles
Search
Showing results (641-650 of 654) with videos related to
Sort By:
Page
of 66
Journal of Medicinal Chemistry
|
January 11, 2008
Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor
Gang Zhao, Andrew J Souers, Martin Voorbach, et al.
Bioorganic & Medicinal Chemistry
|
May 27, 2008
Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain
Irene Drizin, Robert J Gregg, Marc J C Scanio, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 26, 2006
Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: the effects of chirality on substituted indan-1-ylamines
Andrew J Souers, Rajesh R Iyengar, Andrew S Judd, et al.
Journal of Medicinal Chemistry
|
October 27, 2006
Optimization of chromone-2-carboxamide melanin concentrating hormone receptor 1 antagonists: assessment of potency, efficacy, and cardiovascular safety
John K Lynch, Jennifer C Freeman, Andrew S Judd, et al.
International Journal for Parasitology
|
April 1, 2020
Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned
Ryan Choi, Matthew A Hulverson, Wenlin Huang, et al.
Journal of Medicinal Chemistry
|
January 8, 2008
Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain
Michael E Kort, Irene Drizin, Robert J Gregg, et al.
Journal of Medicinal Chemistry
|
December 8, 2006
Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction
Meena V Patel, Teodozyj Kolasa, Kathleen Mortell, et al.
Journal of Medicinal Chemistry
|
January 24, 2012
Identification and preliminary characterization of a potent, safe, and orally efficacious inhibitor of acyl-CoA:diacylglycerol acyltransferase 1
Vince S C Yeh, David W A Beno, Sevan Brodjian, et al.
Molecular Cancer Therapeutics
|
March 31, 2021
Expanding the Repertoire for "Large Small Molecules": Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers
Ahmed Hamed Salem, Zhi-Fu Tao, Orlando F Bueno, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
May 3, 2007
ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models
Cherrie K Donawho, Yan Luo, Yanping Luo, et al.
Page
of 66