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ACS Chemical Biology|December 27, 2021
Mechanistic Insights into a CDK9 Inhibitor Via Orthogonal Proteomics MethodsJ Adam Hendricks, Nigel Beaton, Alexey Chernobrovkin, et al.Nature Communications|July 1, 2021
RAS-inhibiting biologics identify and probe druggable pockets including an SII-α3 allosteric siteKatarzyna Z Haza, Heather L Martin, Ajinkya Rao, et al.Oncotarget|February 9, 2017
Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastasesPeter J Webster, Anna T Littlejohns, Hannah J Gaunt, et al.Insect Molecular Biology|February 13, 2013
The characterization of the Phlebotomus papatasi transcriptomeJ Abrudan, M Ramalho-Ortigão, S O'Neil, et al.Chemistry & Biology|July 30, 2013
PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signalingXinming Cai, Yongyao Xu, Atwood K Cheung, et al.Journal of Medicinal Chemistry|July 13, 2013
Identification of NVP-TNKS656: the use of structure-efficiency relationships to generate a highly potent, selective, and orally active tankyrase inhibitorMichael D Shultz, Atwood K Cheung, Christina A Kirby, et al.Journal of Medicinal Chemistry|November 9, 2018
Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA)Atwood K Cheung, Brian Hurley, Ryan Kerrigan, et al.Bioorganic & Medicinal Chemistry Letters|July 28, 2020
Optimization of a series of potent, selective and orally bioavailable SYK inhibitorsNeil P Grimster, Lakshmaiah Gingipalli, Bernard Barlaam, et al.Annals of Oncology : Official Journal of the European Society for Medical Oncology|April 20, 2016
Tumor heterogeneity of fibroblast growth factor receptor 3 (FGFR3) mutations in invasive bladder cancer: implications for perioperative anti-FGFR3 treatmentD Pouessel, Y Neuzillet, L S Mertens, et al.Nature Cell Biology|July 14, 2015
An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genesGabrielle Wheway, Miriam Schmidts, Dorus A Mans, et al.Pageof 22