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Medrxiv : the Preprint Server for Health Sciences|December 3, 2025
THRIVEair: A community-based air monitoring network design in a pollution-burdened Philadelphia neighborhood to advance environmental justiceSheila Tripathy, Lisa Frueh, Karlin Moore, et al.Journal of Medicinal Chemistry|November 4, 2014
Inhibitors of β-site amyloid precursor protein cleaving enzyme (BACE1): identification of (S)-7-(2-fluoropyridin-3-yl)-3-((3-methyloxetan-3-yl)ethynyl)-5'H-spiro[chromeno[2,3-b]pyridine-5,4'-oxazol]-2'-amine (AMG-8718)Thomas A Dineen, Kui Chen, Alan C Cheng, et al.The Journal of Cell Biology|May 6, 2020
RIM-binding protein couples synaptic vesicle recruitment to release sitesAstrid G Petzoldt, Torsten W B Götz, Jan Heiner Driller, et al.Elife|August 15, 2015
A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zonesMatthias Siebert, Mathias A Böhme, Jan H Driller, et al.Journal of Medicinal Chemistry|November 13, 2014
Lead optimization and modulation of hERG activity in a series of aminooxazoline xanthene β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitorsOleg Epstein, Marian C Bryan, Alan C Cheng, et al.Nature Neuroscience|August 16, 2016
Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca(2+) channel-vesicle couplingMathias A Böhme, Christina Beis, Suneel Reddy-Alla, et al.Nature Communications|January 2, 2025
Blobby is a synaptic active zone assembly protein required for memory in DrosophilaJ Lützkendorf, T Matkovic-Rachid, S Liu, et al.Nature Communications|October 17, 2015
Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and functionKarzan Muhammad, Suneel Reddy-Alla, Jan H Driller, et al.Journal of Medicinal Chemistry|June 29, 2011
From fragment screening to in vivo efficacy: optimization of a series of 2-aminoquinolines as potent inhibitors of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)Yuan Cheng, Ted C Judd, Michael D Bartberger, et al.Journal of Medicinal Chemistry|January 11, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. Discovery of a novel tool compound for in vivo proof-of-conceptKate S Ashton, Kristin L Andrews, Marian C Bryan, et al.Pageof 26