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Diabetes, Obesity & Metabolism|August 1, 2019
A novel specific peroxisome proliferator-activated receptor γ (PPARγ) modulator YR4-42 ameliorates hyperglycaemia and dyslipidaemia and hepatic steatosis in diet-induced obese miceYi Huan, Xuan Pan, Jun Peng, et al.
Frontiers in Pharmacology|March 21, 2022
<i>Morus alba</i> L. (Sangzhi) Alkaloids Promote Insulin Secretion, Restore Diabetic β-Cell Function by Preventing Dedifferentiation and ApoptosisLei Lei, Yi Huan, Quan Liu, et al.
ACS Omega|August 18, 2025
Integration of Metabolomics, Transcriptomics, and 16s rRNA Sequencing Reveals the Mechanism of <i>L.</i> (Sangzhi) Alkaloids (SZ-A) in Improving Cholesterol Metabolism in Diabetic RatsCaina Li, Yuting Ma, Shengyu Wen, et al.
Frontiers in Medicine|June 26, 2023
<i>New anti-diabetic drug Morus alba L.</i> (Sangzhi) alkaloids (SZ-A) improves diabetic nephropathy through ameliorating inflammation and fibrosis in diabetic ratsCaina Li, Quan Liu, Wenming Ji, et al.
Diabetes, Obesity & Metabolism|March 18, 2024
The GPR40 novel agonist SZZ15-11 improves non-alcoholic fatty liver disease by activating the AMPK pathway and restores metabolic homeostasis in diet-induced obese miceLei Lei, Xuefeng Gao, Jiayu Zhai, et al.
Biochemical and Biophysical Research Communications|December 7, 2025
Global Sirt5 deletion reshapes gut microbiota and impairs glucose metabolism in high-fat diet-induced obese miceHui Cao, Kejia Xu, Xiaojue Li, et al.
International Journal of Molecular Sciences|December 23, 2022
Voglibose Regulates the Secretion of GLP-1 Accompanied by Amelioration of Ileal Inflammatory Damage and Endoplasmic Reticulum Stress in Diabetic KKAy MiceYaxin Fu, Wenming Ji, Quan Liu, et al.
ACS Pharmacology & Translational Science|January 15, 2026
Beneficial Effects of a Novel Fructose-1,6-Bisphosphatase Inhibitor Cpd96 on Insulin Secretion in Type 2 DiabetesKejia Xu, Jiaxuan Zhao, Liran Lei, et al.
Scientific Reports|June 30, 2017
The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivoYi Huan, Qian Jiang, Gang Li, et al.
Biochemical Pharmacology|January 23, 2018
Glutazumab, a novel long-lasting GLP-1/anti-GLP-1R antibody fusion protein, exerts anti-diabetic effects through targeting dual receptor binding sitesCaina Li, Miaomiao Yang, Xiaofeng Wang, et al.
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