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The FEBS Journal|October 26, 2011
Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazolesMeera Gurumurthy, Tathagata Mukherjee, Cynthia S Dowd, et al.
Nature Communications|April 5, 2020
Pyrazinamide triggers degradation of its target aspartate decarboxylasePooja Gopal, Jickky Palmae Sarathy, Michelle Yee, et al.
The Journal of Experimental Medicine|July 19, 2018
Impact of immunopathology on the antituberculous activity of pyrazinamideLandry Blanc, Jansy Passiflora Sarathy, Nadine Alvarez Cabrera, et al.
Journal of Medicinal Chemistry|February 13, 2009
Structure-activity relationships of antitubercular nitroimidazoles. 2. Determinants of aerobic activity and quantitative structure-activity relationshipsPilho Kim, Sunhee Kang, Helena I Boshoff, et al.
ACS Infectious Diseases|June 2, 2026
Cytochrome P450-Mediated Metabolism of Antimycobacterial Nα-Aroyl-N-aryl-phenylalanine AmidesJohannes Doering, Erik Meerz, Rüdiger W Seidel, et al.
Scientific Reports|November 16, 2019
Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesisWuan-Geok Saw, Mu-Lu Wu, Priya Ragunathan, et al.
Plos One|August 21, 2014
Pharmacokinetics-pharmacodynamics analysis of bicyclic 4-nitroimidazole analogs in a murine model of tuberculosisSuresh B Lakshminarayana, Helena I M Boshoff, Joseph Cherian, et al.
European Journal of Medicinal Chemistry|November 18, 2022
Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatizationMiriam Girardini, Francesca Ferlenghi, Giannamaria Annunziato, et al.
Proceedings of the National Academy of Sciences of the United States of America|September 7, 2019
Phase variation in Mycobacterium tuberculosis glpK produces transiently heritable drug toleranceHassan Safi, Pooja Gopal, Subramanya Lingaraju, et al.
Microbiology Spectrum|November 20, 2023
GaMF1.39's antibiotic efficacy and its enhanced antitubercular activity in combination with clofazimine, Telacebec, ND-011992, or TBAJ-876Priya Ragunathan, Pearly Shuyi Ng, Samsher Singh, et al.
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