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Journal of Medicinal Chemistry|July 26, 2022
Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306Janek Szychowski, Robert Papp, Evelyne Dietrich, et al.Journal of Medicinal Chemistry|June 14, 2011
Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemiaRenata M Oballa, Liette Belair, W Cameron Black, et al.Bioorganic & Medicinal Chemistry Letters|January 30, 2008
The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin KJacques Yves Gauthier, Nathalie Chauret, Wanda Cromlish, et al.Bioorganic & Medicinal Chemistry Letters|January 12, 2010
The discovery of MK-0674, an orally bioavailable cathepsin K inhibitorElise Isabel, Kevin P Bateman, Nathalie Chauret, et al.Journal of Medicinal Chemistry|February 1, 2024
Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500)W Cameron Black, Abbas Abdoli, Xiuli An, et al.Journal of Medicinal Chemistry|May 16, 2025
Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 InhibitorFrédéric Vallée, Matias Casás-Selves, Monica Bubenik, et al.Journal of Medicinal Chemistry|September 8, 2025
The Discovery of RP-2119: A Potent, Selective, and Orally Bioavailable Polθ ATPase InhibitorPhilippe Mochirian, Robert Papp, Marie-Claude Mathieu, et al.Journal of Medicinal Chemistry|September 20, 2022
Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of PolθMonica Bubenik, Pavel Mader, Philippe Mochirian, et al.Pageof 7