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Biorxiv : the Preprint Server for Biology|March 31, 2025
The Endo-GeneScreen Platform Identifies Drug-Like Probes that Regulate Endogenous Protein Levels within Physiological ContextsPreston Samowitz, Laszlo Radnai, Thomas Vaissiere, et al.
Nature Communications|December 9, 2025
The Endo-GeneScreen platform identifies drug-like probes that regulate endogenous protein levels within physiological contextsPreston Samowitz, Laszlo Radnai, Thomas Vaissiere, et al.
Elife|April 8, 2022
Endogenous Syngap1 alpha splice forms promote cognitive function and seizure protectionMurat Kilinc, Vineet Arora, Thomas K Creson, et al.
Angiogenesis|July 9, 2016
Prostate-specific membrane antigen (PSMA)-mediated laminin proteolysis generates a pro-angiogenic peptideRebecca E Conway, Camilo Rojas, Jesse Alt, et al.
Nanotheranostics|January 3, 2022
Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosisKristen R Hollinger, Anjali Sharma, Carolyn Tallon, et al.
Journal of Medicinal Chemistry|April 17, 2020
Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer's DiseaseMichal Šála, Kristen R Hollinger, Ajit G Thomas, et al.
Journal of Medicinal Chemistry|May 31, 2012
Design, synthesis, and pharmacological evaluation of glutamate carboxypeptidase II (GCPII) inhibitors based on thioalkylbenzoic acid scaffoldsDoris Stoermer, Dilrukshi Vitharana, Niyada Hin, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 22, 2012
Inhibition of glutamate carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosisKristen A Rahn, Crystal C Watkins, Jesse Alt, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|March 14, 2019
Correction: JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stressXiaolei Zhu, Michael T Nedelcovych, Ajit G Thomas, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|August 22, 2018
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stressXiaolei Zhu, Michael T Nedelcovych, Ajit G Thomas, et al.
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